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3b7x

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[[Image:3b7x.png|left|200px]]
 
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{{STRUCTURE_3b7x| PDB=3b7x | SCENE= }}
{{STRUCTURE_3b7x| PDB=3b7x | SCENE= }}
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===Crystal structure of human FK506-Binding Protein 6===
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===Crystal structure of human FK506-Binding Protein 6===
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==Disease==
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[[http://www.uniprot.org/uniprot/FKBP6_HUMAN FKBP6_HUMAN]] Note=FKBP6 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of FKBP6 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.
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==Function==
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[[http://www.uniprot.org/uniprot/FKBP6_HUMAN FKBP6_HUMAN]] PPIases accelerate the folding of proteins.
==About this Structure==
==About this Structure==

Revision as of 19:22, 24 March 2013

Template:STRUCTURE 3b7x

Contents

Crystal structure of human FK506-Binding Protein 6

Disease

[FKBP6_HUMAN] Note=FKBP6 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of FKBP6 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease.

Function

[FKBP6_HUMAN] PPIases accelerate the folding of proteins.

About this Structure

3b7x is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Proteopedia Page Contributors and Editors (what is this?)

OCA

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