1nyx
From Proteopedia
(Difference between revisions)
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| - | [[Image:1nyx.png|left|200px]] | ||
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{{STRUCTURE_1nyx| PDB=1nyx | SCENE= }} | {{STRUCTURE_1nyx| PDB=1nyx | SCENE= }} | ||
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===Ligand binding domain of the human peroxisome proliferator activated receptor gamma in complex with an agonist=== | ===Ligand binding domain of the human peroxisome proliferator activated receptor gamma in complex with an agonist=== | ||
| + | {{ABSTRACT_PUBMED_12672231}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/PPAT_HUMAN PPAT_HUMAN]] Dephosphorylates receptor tyrosine-protein kinase erbB-4 and inhibits the ligand-induced proteolytic cleavage.<ref>PMID:15219672</ref> | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:012672231</ref><references group="xtra"/> | + | <ref group="xtra">PMID:012672231</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Deussen, H J.]] | [[Category: Deussen, H J.]] | ||
Revision as of 19:28, 24 March 2013
Contents |
Ligand binding domain of the human peroxisome proliferator activated receptor gamma in complex with an agonist
Template:ABSTRACT PUBMED 12672231
Function
[PPAT_HUMAN] Dephosphorylates receptor tyrosine-protein kinase erbB-4 and inhibits the ligand-induced proteolytic cleavage.[1]
About this Structure
1nyx is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Ebdrup S, Pettersson I, Rasmussen HB, Deussen HJ, Frost Jensen A, Mortensen SB, Fleckner J, Pridal L, Nygaard L, Sauerberg P. Synthesis and biological and structural characterization of the dual-acting peroxisome proliferator-activated receptor alpha/gamma agonist ragaglitazar. J Med Chem. 2003 Apr 10;46(8):1306-17. PMID:12672231 doi:10.1021/jm021027r
- ↑ Fleisig H, El-Din El-Husseini A, Vincent SR. Regulation of ErbB4 phosphorylation and cleavage by a novel histidine acid phosphatase. Neuroscience. 2004;127(1):91-100. PMID:15219672 doi:10.1016/j.neuroscience.2004.04.060
