3kxu
From Proteopedia
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| - | [[Image:3kxu.png|left|200px]] | ||
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{{STRUCTURE_3kxu| PDB=3kxu | SCENE= }} | {{STRUCTURE_3kxu| PDB=3kxu | SCENE= }} | ||
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===Crystal structure of human ferritin FTL498InsTC pathogenic mutant=== | ===Crystal structure of human ferritin FTL498InsTC pathogenic mutant=== | ||
| + | {{ABSTRACT_PUBMED_20159981}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/Q6S4P3_HUMAN Q6S4P3_HUMAN]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis (By similarity).[RuleBase:RU000622] | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:020159981</ref><references group="xtra"/> | + | <ref group="xtra">PMID:020159981</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arosio, P.]] | [[Category: Arosio, P.]] | ||
Revision as of 20:11, 24 March 2013
Contents |
Crystal structure of human ferritin FTL498InsTC pathogenic mutant
Template:ABSTRACT PUBMED 20159981
Function
[Q6S4P3_HUMAN] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis (By similarity).[RuleBase:RU000622]
About this Structure
3kxu is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Luscieti S, Santambrogio P, Langlois d'Estaintot B, Granier T, Cozzi A, Poli M, Gallois B, Finazzi D, Cattaneo A, Levi S, Arosio P. Mutant ferritin L-chains that cause neurodegeneration act in a dominant-negative manner to reduce ferritin iron incorporation. J Biol Chem. 2010 Apr 16;285(16):11948-57. Epub 2010 Feb 16. PMID:20159981 doi:10.1074/jbc.M109.096404
