1p9j
From Proteopedia
(Difference between revisions)
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| - | [[Image:1p9j.png|left|200px]] | ||
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{{STRUCTURE_1p9j| PDB=1p9j | SCENE= }} | {{STRUCTURE_1p9j| PDB=1p9j | SCENE= }} | ||
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===Solution structure and dynamics of the EGF/TGF-alpha chimera T1E=== | ===Solution structure and dynamics of the EGF/TGF-alpha chimera T1E=== | ||
| + | {{ABSTRACT_PUBMED_12869572}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/TGFA_HUMAN TGFA_HUMAN]] TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar. | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:012869572</ref><references group="xtra"/> | + | <ref group="xtra">PMID:012869572</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Ingen, H Van.]] | [[Category: Ingen, H Van.]] | ||
Revision as of 20:52, 24 March 2013
Contents |
Solution structure and dynamics of the EGF/TGF-alpha chimera T1E
Template:ABSTRACT PUBMED 12869572
Function
[TGFA_HUMAN] TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
About this Structure
1p9j is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
See Also
Reference
- Wingens M, Walma T, van Ingen H, Stortelers C, van Leeuwen JE, van Zoelen EJ, Vuister GW. Structural analysis of an epidermal growth factor/transforming growth factor-alpha chimera with unique ErbB binding specificity. J Biol Chem. 2003 Oct 3;278(40):39114-23. Epub 2003 Jul 16. PMID:12869572 doi:10.1074/jbc.M305603200
