1lgn

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m (Protected "1lgn" [edit=sysop:move=sysop])
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[[Image:1lgn.png|left|200px]]
 
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{{STRUCTURE_1lgn| PDB=1lgn | SCENE= }}
{{STRUCTURE_1lgn| PDB=1lgn | SCENE= }}
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===DECAMERIC DAMP COMPLEX OF HUMAN SERUM AMYLOID P COMPONENT===
===DECAMERIC DAMP COMPLEX OF HUMAN SERUM AMYLOID P COMPONENT===
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{{ABSTRACT_PUBMED_9217261}}
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{{ABSTRACT_PUBMED_9217261}}
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==Disease==
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[[http://www.uniprot.org/uniprot/SAMP_HUMAN SAMP_HUMAN]] Note=SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits.
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==Function==
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[[http://www.uniprot.org/uniprot/SAMP_HUMAN SAMP_HUMAN]] Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:009217261</ref><references group="xtra"/>
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<ref group="xtra">PMID:009217261</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Hohenester, E.]]
[[Category: Hohenester, E.]]

Revision as of 21:22, 24 March 2013

Template:STRUCTURE 1lgn

Contents

DECAMERIC DAMP COMPLEX OF HUMAN SERUM AMYLOID P COMPONENT

Template:ABSTRACT PUBMED 9217261

Disease

[SAMP_HUMAN] Note=SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits.

Function

[SAMP_HUMAN] Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.

About this Structure

1lgn is a 5 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hohenester E, Hutchinson WL, Pepys MB, Wood SP. Crystal structure of a decameric complex of human serum amyloid P component with bound dAMP. J Mol Biol. 1997 Jun 20;269(4):570-8. PMID:9217261 doi:10.1006/jmbi.1997.1075

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OCA

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