3h2u
From Proteopedia
(Difference between revisions)
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| - | [[Image:3h2u.png|left|200px]] | ||
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{{STRUCTURE_3h2u| PDB=3h2u | SCENE= }} | {{STRUCTURE_3h2u| PDB=3h2u | SCENE= }} | ||
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===Human raver1 RRM1, RRM2, and RRM3 domains in complex with human vinculin tail domain Vt=== | ===Human raver1 RRM1, RRM2, and RRM3 domains in complex with human vinculin tail domain Vt=== | ||
| + | {{ABSTRACT_PUBMED_19523901}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/RAVR1_HUMAN RAVR1_HUMAN]] Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA (By similarity). | ||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:019523901</ref><references group="xtra"/> | + | <ref group="xtra">PMID:019523901</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Izard, T.]] | [[Category: Izard, T.]] | ||
Revision as of 22:13, 24 March 2013
Contents |
Human raver1 RRM1, RRM2, and RRM3 domains in complex with human vinculin tail domain Vt
Template:ABSTRACT PUBMED 19523901
Function
[RAVR1_HUMAN] Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA (By similarity).
About this Structure
3h2u is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Lee JH, Rangarajan ES, Yogesha SD, Izard T. Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions. Structure. 2009 Jun 10;17(6):833-42. PMID:19523901 doi:S0969-2126(09)00193-2
