2cov
From Proteopedia
(New page: 200px<br /><applet load="2cov" size="350" color="white" frame="true" align="right" spinBox="true" caption="2cov, resolution 1.25Å" /> '''Crystal structure of...) |
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==Overview== | ==Overview== | ||
| - | Here, we present the crystal structure of the family 31 | + | Here, we present the crystal structure of the family 31 carbohydrate-binding module (CBM) of beta-1,3-xylanase from Alcaligenes sp. strain XY-234 (AlcCBM31) determined at a resolution of 1.25A. The AlcCBM31 shows affinity with only beta-1,3-xylan. The AlcCBM31 molecule makes a beta-sandwich structure composed of eight beta-strands with a typical immunoglobulin fold and contains two intra-molecular disulfide bonds. The folding topology of AlcCBM31 differs from that of the large majority of other CBMs, in which eight beta-strands comprise a beta-sandwich structure with a typical jelly-roll fold. AlcCBM31 shows structural similarity with CBM structures of family 34 and family 9, which also adopt structures based on immunoglobulin folds. |
==About this Structure== | ==About this Structure== | ||
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[[Category: family 31 cbm]] | [[Category: family 31 cbm]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:50:56 2008'' |
Revision as of 14:50, 21 February 2008
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Crystal structure of CBM31 from beta-1,3-xylanase
Overview
Here, we present the crystal structure of the family 31 carbohydrate-binding module (CBM) of beta-1,3-xylanase from Alcaligenes sp. strain XY-234 (AlcCBM31) determined at a resolution of 1.25A. The AlcCBM31 shows affinity with only beta-1,3-xylan. The AlcCBM31 molecule makes a beta-sandwich structure composed of eight beta-strands with a typical immunoglobulin fold and contains two intra-molecular disulfide bonds. The folding topology of AlcCBM31 differs from that of the large majority of other CBMs, in which eight beta-strands comprise a beta-sandwich structure with a typical jelly-roll fold. AlcCBM31 shows structural similarity with CBM structures of family 34 and family 9, which also adopt structures based on immunoglobulin folds.
About this Structure
2COV is a Single protein structure of sequence from Alcaligenes sp.. Full crystallographic information is available from OCA.
Reference
The first crystal structure of a family 31 carbohydrate-binding module with affinity to beta-1,3-xylan., Hashimoto H, Tamai Y, Okazaki F, Tamaru Y, Shimizu T, Araki T, Sato M, FEBS Lett. 2005 Aug 15;579(20):4324-8. PMID:16061225
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