1gtq

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m (Protected "1gtq" [edit=sysop:move=sysop])
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[[Image:1gtq.png|left|200px]]
 
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{{STRUCTURE_1gtq| PDB=1gtq | SCENE= }}
{{STRUCTURE_1gtq| PDB=1gtq | SCENE= }}
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===6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE===
===6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE===
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{{ABSTRACT_PUBMED_8137809}}
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{{ABSTRACT_PUBMED_8137809}}
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==Disease==
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[[http://www.uniprot.org/uniprot/PTPS_RAT PTPS_RAT]] Note=Deficiency leads to phenylketonuria.
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==Function==
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[[http://www.uniprot.org/uniprot/PTPS_RAT PTPS_RAT]] Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:008137809</ref><references group="xtra"/>
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<ref group="xtra">PMID:008137809</ref><references group="xtra"/><references/>
[[Category: 6-pyruvoyltetrahydropterin synthase]]
[[Category: 6-pyruvoyltetrahydropterin synthase]]
[[Category: Rattus rattus]]
[[Category: Rattus rattus]]

Revision as of 04:57, 25 March 2013

Template:STRUCTURE 1gtq

Contents

6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE

Template:ABSTRACT PUBMED 8137809

Disease

[PTPS_RAT] Note=Deficiency leads to phenylketonuria.

Function

[PTPS_RAT] Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin.

About this Structure

1gtq is a 2 chain structure with sequence from Rattus rattus. Full crystallographic information is available from OCA.

Reference

  • Nar H, Huber R, Heizmann CW, Thony B, Burgisser D. Three-dimensional structure of 6-pyruvoyl tetrahydropterin synthase, an enzyme involved in tetrahydrobiopterin biosynthesis. EMBO J. 1994 Mar 15;13(6):1255-62. PMID:8137809

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OCA

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