2d7e
From Proteopedia
(New page: 200px<br /><applet load="2d7e" size="450" color="white" frame="true" align="right" spinBox="true" caption="2d7e, resolution 2.5Å" /> '''Crystal structure of ...) |
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| - | [[Image:2d7e.jpg|left|200px]]<br /><applet load="2d7e" size=" | + | [[Image:2d7e.jpg|left|200px]]<br /><applet load="2d7e" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="2d7e, resolution 2.5Å" /> | caption="2d7e, resolution 2.5Å" /> | ||
'''Crystal structure of N-terminal domain of PriA from E.coli'''<br /> | '''Crystal structure of N-terminal domain of PriA from E.coli'''<br /> | ||
==Overview== | ==Overview== | ||
| - | PriA, a DEXH-type DNA helicase, binds specifically to the 3' end of DNA | + | PriA, a DEXH-type DNA helicase, binds specifically to the 3' end of DNA through its N-terminal domain, and is a candidate sensor protein that recognizes arrested DNA replication forks in bacteria. We crystallized an N-terminal fragment of PriA in the absence and the presence of oligonucleotides to elucidate the structural basis for the specific recognition of the 3' terminus of DNA. |
==About this Structure== | ==About this Structure== | ||
| - | 2D7E is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http:// | + | 2D7E is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D7E OCA]. |
==Reference== | ==Reference== | ||
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[[Category: inter-twined]] | [[Category: inter-twined]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:55:57 2008'' |
Revision as of 14:55, 21 February 2008
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Crystal structure of N-terminal domain of PriA from E.coli
Overview
PriA, a DEXH-type DNA helicase, binds specifically to the 3' end of DNA through its N-terminal domain, and is a candidate sensor protein that recognizes arrested DNA replication forks in bacteria. We crystallized an N-terminal fragment of PriA in the absence and the presence of oligonucleotides to elucidate the structural basis for the specific recognition of the 3' terminus of DNA.
About this Structure
2D7E is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
Crystallization and preliminary crystallographic analysis of the N-terminal domain of PriA from Escherichia coli., Sasaki K, Ose T, Tanaka T, Mizukoshi T, Ishigaki T, Maenaka K, Masai H, Kohda D, Biochim Biophys Acta. 2006 Jan;1764(1):157-60. Epub 2005 Oct 3. PMID:16226927
Page seeded by OCA on Thu Feb 21 16:55:57 2008
