2d7h
From Proteopedia
(New page: 200px<br /><applet load="2d7h" size="450" color="white" frame="true" align="right" spinBox="true" caption="2d7h, resolution 3.0Å" /> '''Crystal structure of ...) |
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| - | [[Image:2d7h.jpg|left|200px]]<br /><applet load="2d7h" size=" | + | [[Image:2d7h.jpg|left|200px]]<br /><applet load="2d7h" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="2d7h, resolution 3.0Å" /> | caption="2d7h, resolution 3.0Å" /> | ||
'''Crystal structure of the ccc complex of the N-terminal domain of PriA'''<br /> | '''Crystal structure of the ccc complex of the N-terminal domain of PriA'''<br /> | ||
==Overview== | ==Overview== | ||
| - | PriA, a DEXH-type DNA helicase, binds specifically to the 3' end of DNA | + | PriA, a DEXH-type DNA helicase, binds specifically to the 3' end of DNA through its N-terminal domain, and is a candidate sensor protein that recognizes arrested DNA replication forks in bacteria. We crystallized an N-terminal fragment of PriA in the absence and the presence of oligonucleotides to elucidate the structural basis for the specific recognition of the 3' terminus of DNA. |
==About this Structure== | ==About this Structure== | ||
| - | 2D7H is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with DCM as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http:// | + | 2D7H is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=DCM:'>DCM</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D7H OCA]. |
==Reference== | ==Reference== | ||
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[[Category: protein-dna complex]] | [[Category: protein-dna complex]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:55:57 2008'' |
Revision as of 14:55, 21 February 2008
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Crystal structure of the ccc complex of the N-terminal domain of PriA
Overview
PriA, a DEXH-type DNA helicase, binds specifically to the 3' end of DNA through its N-terminal domain, and is a candidate sensor protein that recognizes arrested DNA replication forks in bacteria. We crystallized an N-terminal fragment of PriA in the absence and the presence of oligonucleotides to elucidate the structural basis for the specific recognition of the 3' terminus of DNA.
About this Structure
2D7H is a Single protein structure of sequence from Escherichia coli with as ligand. Full crystallographic information is available from OCA.
Reference
Crystallization and preliminary crystallographic analysis of the N-terminal domain of PriA from Escherichia coli., Sasaki K, Ose T, Tanaka T, Mizukoshi T, Ishigaki T, Maenaka K, Masai H, Kohda D, Biochim Biophys Acta. 2006 Jan;1764(1):157-60. Epub 2005 Oct 3. PMID:16226927
Page seeded by OCA on Thu Feb 21 16:55:57 2008
