1dug

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[[Image:1dug.png|left|200px]]
 
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{{STRUCTURE_1dug| PDB=1dug | SCENE= }}
{{STRUCTURE_1dug| PDB=1dug | SCENE= }}
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===STRUCTURE OF THE FIBRINOGEN G CHAIN INTEGRIN BINDING AND FACTOR XIIIA CROSSLINKING SITES OBTAINED THROUGH CARRIER PROTEIN DRIVEN CRYSTALLIZATION===
===STRUCTURE OF THE FIBRINOGEN G CHAIN INTEGRIN BINDING AND FACTOR XIIIA CROSSLINKING SITES OBTAINED THROUGH CARRIER PROTEIN DRIVEN CRYSTALLIZATION===
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{{ABSTRACT_PUBMED_10631982}}
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{{ABSTRACT_PUBMED_10631982}}
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==Function==
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[[http://www.uniprot.org/uniprot/GST26_SCHJA GST26_SCHJA]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut.
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:010631982</ref><references group="xtra"/>
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<ref group="xtra">PMID:010631982</ref><references group="xtra"/><references/>
[[Category: Glutathione transferase]]
[[Category: Glutathione transferase]]
[[Category: Schistosoma japonicum]]
[[Category: Schistosoma japonicum]]

Revision as of 06:55, 25 March 2013

Template:STRUCTURE 1dug

Contents

STRUCTURE OF THE FIBRINOGEN G CHAIN INTEGRIN BINDING AND FACTOR XIIIA CROSSLINKING SITES OBTAINED THROUGH CARRIER PROTEIN DRIVEN CRYSTALLIZATION

Template:ABSTRACT PUBMED 10631982

Function

[GST26_SCHJA] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. GST isoenzymes appear to play a central role in the parasite detoxification system. Other functions are also suspected including a role in increasing the solubility of haematin in the parasite gut.

About this Structure

1dug is a 2 chain structure with sequence from Schistosoma japonicum. Full crystallographic information is available from OCA.

See Also

Reference

  • Ware S, Donahue JP, Hawiger J, Anderson WF. Structure of the fibrinogen gamma-chain integrin binding and factor XIIIa cross-linking sites obtained through carrier protein driven crystallization. Protein Sci. 1999 Dec;8(12):2663-71. PMID:10631982

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