2uxx
From Proteopedia
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| - | [[Image:2uxx.png|left|200px]] | ||
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{{STRUCTURE_2uxx| PDB=2uxx | SCENE= }} | {{STRUCTURE_2uxx| PDB=2uxx | SCENE= }} | ||
| - | + | ===Human LSD1 Histone Demethylase-CoREST in complex with an FAD- tranylcypromine adduct=== | |
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{{ABSTRACT_PUBMED_17569509}} | {{ABSTRACT_PUBMED_17569509}} | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:017569509</ref><ref group="xtra">PMID:016885027</ref><references group="xtra"/> | + | <ref group="xtra">PMID:017569509</ref><ref group="xtra">PMID:016885027</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Cole, P A.]] | [[Category: Cole, P A.]] | ||
Revision as of 07:43, 27 March 2013
Contents |
Human LSD1 Histone Demethylase-CoREST in complex with an FAD- tranylcypromine adduct
Template:ABSTRACT PUBMED 17569509
About this Structure
2uxx is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Yang M, Culhane JC, Szewczuk LM, Jalili P, Ball HL, Machius M, Cole PA, Yu H. Structural basis for the inhibition of the LSD1 histone demethylase by the antidepressant trans-2-phenylcyclopropylamine. Biochemistry. 2007 Jul 10;46(27):8058-65. Epub 2007 Jun 15. PMID:17569509 doi:10.1021/bi700664y
- Yang M, Gocke CB, Luo X, Borek D, Tomchick DR, Machius M, Otwinowski Z, Yu H. Structural basis for CoREST-dependent demethylation of nucleosomes by the human LSD1 histone demethylase. Mol Cell. 2006 Aug 4;23(3):377-87. PMID:16885027 doi:http://dx.doi.org/10.1016/j.molcel.2006.07.012
Categories: Homo sapiens | Cole, P A. | Culhane, J C. | Machius, M. | Yang, M. | Yu, H. | Chromatin demethylation | Chromatin regulator | Corest | Depression | Fad | Histone demethylase | Host-virus interaction | Lsd1 | Nuclear protein | Nucleosome | Oxidoreductase | Oxidoreductase-repressor complex | Phosphorylation | Repressor | Transcription | Transcription regulation | Tranylcypromine
