2dge

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: 200px<br /><applet load="2dge" size="450" color="white" frame="true" align="right" spinBox="true" caption="2dge, resolution 1.50&Aring;" /> '''Crystal structure of...)
Line 1: Line 1:
-
[[Image:2dge.gif|left|200px]]<br /><applet load="2dge" size="450" color="white" frame="true" align="right" spinBox="true"
+
[[Image:2dge.gif|left|200px]]<br /><applet load="2dge" size="350" color="white" frame="true" align="right" spinBox="true"
caption="2dge, resolution 1.50&Aring;" />
caption="2dge, resolution 1.50&Aring;" />
'''Crystal structure of oxidized cytochrome C6A from Arabidopsis thaliana'''<br />
'''Crystal structure of oxidized cytochrome C6A from Arabidopsis thaliana'''<br />
==Overview==
==Overview==
-
Compared with algal and cyanobacterial cytochrome c(6), cytochrome c(6A), from higher plants contains an additional loop of 12 amino acid residues., We have determined the first crystal structure of cytochrome c(6A) from, Arabidopsis thaliana at 1.5 Angstrom resolution in order to help elucidate, its function. The overall structure of cytochrome c(6A) follows the, topology of class I c-type cytochromes in which the heme prosthetic group, covalently binds to Cys16 and Cys19, and the iron has octahedral, coordination with His20 and Met60 as the axial ligands. Two cysteine, residues (Cys67 and Cys73) within the characteristic 12 amino acids loop, form a disulfide bond, contributing to the structural stability of, cytochrome c(6A). Our model provides a chemical basis for the known low, redox potential of cytochrome c(6A) which makes it an unsuitable electron, carrier between cytochrome b(6)f and PSI.
+
Compared with algal and cyanobacterial cytochrome c(6), cytochrome c(6A) from higher plants contains an additional loop of 12 amino acid residues. We have determined the first crystal structure of cytochrome c(6A) from Arabidopsis thaliana at 1.5 Angstrom resolution in order to help elucidate its function. The overall structure of cytochrome c(6A) follows the topology of class I c-type cytochromes in which the heme prosthetic group covalently binds to Cys16 and Cys19, and the iron has octahedral coordination with His20 and Met60 as the axial ligands. Two cysteine residues (Cys67 and Cys73) within the characteristic 12 amino acids loop form a disulfide bond, contributing to the structural stability of cytochrome c(6A). Our model provides a chemical basis for the known low redox potential of cytochrome c(6A) which makes it an unsuitable electron carrier between cytochrome b(6)f and PSI.
==About this Structure==
==About this Structure==
-
2DGE is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana] with ZN and HEM as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2DGE OCA].
+
2DGE is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=HEM:'>HEM</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DGE OCA].
==Reference==
==Reference==
Line 21: Line 21:
[[Category: Nishio, T.]]
[[Category: Nishio, T.]]
[[Category: Oku, T.]]
[[Category: Oku, T.]]
-
[[Category: Park, S.Y.]]
+
[[Category: Park, S Y.]]
[[Category: Satoh, T.]]
[[Category: Satoh, T.]]
[[Category: Suruga, K.]]
[[Category: Suruga, K.]]
Line 36: Line 36:
[[Category: heme exposure]]
[[Category: heme exposure]]
-
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 09:36:09 2007''
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:58:30 2008''

Revision as of 14:58, 21 February 2008

Image:2dge.gif

2dge, resolution 1.50Å

Drag the structure with the mouse to rotate

Crystal structure of oxidized cytochrome C6A from Arabidopsis thaliana

Overview

Compared with algal and cyanobacterial cytochrome c(6), cytochrome c(6A) from higher plants contains an additional loop of 12 amino acid residues. We have determined the first crystal structure of cytochrome c(6A) from Arabidopsis thaliana at 1.5 Angstrom resolution in order to help elucidate its function. The overall structure of cytochrome c(6A) follows the topology of class I c-type cytochromes in which the heme prosthetic group covalently binds to Cys16 and Cys19, and the iron has octahedral coordination with His20 and Met60 as the axial ligands. Two cysteine residues (Cys67 and Cys73) within the characteristic 12 amino acids loop form a disulfide bond, contributing to the structural stability of cytochrome c(6A). Our model provides a chemical basis for the known low redox potential of cytochrome c(6A) which makes it an unsuitable electron carrier between cytochrome b(6)f and PSI.

About this Structure

2DGE is a Single protein structure of sequence from Arabidopsis thaliana with and as ligands. Full crystallographic information is available from OCA.

Reference

Crystal structure of oxidized cytochrome c(6A) from Arabidopsis thaliana., Chida H, Yokoyama T, Kawai F, Nakazawa A, Akazaki H, Takayama Y, Hirano T, Suruga K, Satoh T, Yamada S, Kawachi R, Unzai S, Nishio T, Park SY, Oku T, FEBS Lett. 2006 Jun 26;580(15):3763-8. Epub 2006 Jun 9. PMID:16777100

Page seeded by OCA on Thu Feb 21 16:58:30 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2dge"
Personal tools