1o0r

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===Crystal structure of the catalytic domain of bovine beta1,4-galactosyltransferase complex with UDP-galactose===
===Crystal structure of the catalytic domain of bovine beta1,4-galactosyltransferase complex with UDP-galactose===
{{ABSTRACT_PUBMED_12051854}}
{{ABSTRACT_PUBMED_12051854}}
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==Function==
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[[http://www.uniprot.org/uniprot/B4GT1_BOVIN B4GT1_BOVIN]] The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. The cell surface form functions as a recognition molecule during a variety of cell to cell and cell to matrix interactions, as those occurring during development and egg fertilization, by binding to specific oligosaccharide ligands on opposing cells or in the extracellular matrix.
==About this Structure==
==About this Structure==
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[[1o0r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermomicrobium_roseum Thermomicrobium roseum]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1kyb 1kyb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O0R OCA].
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[[1o0r]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1kyb 1kyb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O0R OCA].
==See Also==
==See Also==
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==Reference==
==Reference==
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<ref group="xtra">PMID:012051854</ref><references group="xtra"/>
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<ref group="xtra">PMID:012051854</ref><references group="xtra"/><references/>
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[[Category: Bos taurus]]
[[Category: N-acetyllactosamine synthase]]
[[Category: N-acetyllactosamine synthase]]
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[[Category: Thermomicrobium roseum]]
 
[[Category: Balaji, P V.]]
[[Category: Balaji, P V.]]
[[Category: Qasba, P K.]]
[[Category: Qasba, P K.]]

Revision as of 08:39, 27 March 2013

Template:STRUCTURE 1o0r

Contents

Crystal structure of the catalytic domain of bovine beta1,4-galactosyltransferase complex with UDP-galactose

Template:ABSTRACT PUBMED 12051854

Function

[B4GT1_BOVIN] The Golgi complex form catalyzes the production of lactose in the lactating mammary gland and could also be responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. The cell surface form functions as a recognition molecule during a variety of cell to cell and cell to matrix interactions, as those occurring during development and egg fertilization, by binding to specific oligosaccharide ligands on opposing cells or in the extracellular matrix.

About this Structure

1o0r is a 2 chain structure with sequence from Bos taurus. This structure supersedes the now removed PDB entry 1kyb. Full crystallographic information is available from OCA.

See Also

Reference

  • Ramakrishnan B, Balaji PV, Qasba PK. Crystal structure of beta1,4-galactosyltransferase complex with UDP-Gal reveals an oligosaccharide acceptor binding site. J Mol Biol. 2002 Apr 26;318(2):491-502. PMID:12051854 doi:10.1016/S0022-2836(02)00020-7

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