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2j6h

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===E. COLI GLUCOSAMINE-6-P SYNTHASE IN COMPLEX WITH GLUCOSE-6P AND 5-OXO-L-NORLEUCINE===
===E. COLI GLUCOSAMINE-6-P SYNTHASE IN COMPLEX WITH GLUCOSE-6P AND 5-OXO-L-NORLEUCINE===
{{ABSTRACT_PUBMED_16339762}}
{{ABSTRACT_PUBMED_16339762}}
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==Function==
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[[http://www.uniprot.org/uniprot/GLMS_ECOLI GLMS_ECOLI]] Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:016339762</ref><ref group="xtra">PMID:017322533</ref><references group="xtra"/>
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<ref group="xtra">PMID:016339762</ref><ref group="xtra">PMID:017322533</ref><references group="xtra"/><references/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Golinelli-Pimpaneau, B.]]
[[Category: Golinelli-Pimpaneau, B.]]

Revision as of 08:40, 27 March 2013

Template:STRUCTURE 2j6h

Contents

E. COLI GLUCOSAMINE-6-P SYNTHASE IN COMPLEX WITH GLUCOSE-6P AND 5-OXO-L-NORLEUCINE

Template:ABSTRACT PUBMED 16339762

Function

[GLMS_ECOLI] Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.

About this Structure

2j6h is a 2 chain structure with sequence from Escherichia coli. This structure supersedes the now removed PDB entry 2bpj. Full crystallographic information is available from OCA.

See Also

Reference

  • Mouilleron S, Badet-Denisot MA, Golinelli-Pimpaneau B. Glutamine binding opens the ammonia channel and activates glucosamine-6P synthase. J Biol Chem. 2006 Feb 17;281(7):4404-12. Epub 2005 Dec 9. PMID:16339762 doi:10.1074/jbc.M511689200
  • Mouilleron S, Golinelli-Pimpaneau B. Domain motions of glucosamine-6P synthase: comparison of the anisotropic displacements in the crystals and the catalytic hinge-bending rotation. Protein Sci. 2007 Mar;16(3):485-93. PMID:17322533 doi:16/3/485

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