3vqg

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'''Unreleased structure'''
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{{STRUCTURE_3vqg| PDB=3vqg | SCENE= }}
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===Crystal Structure Analysis of the PDZ Domain Derived from the Tight Junction Regulating Protein===
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The entry 3vqg is ON HOLD until Mar 23 2014
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==Function==
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[[http://www.uniprot.org/uniprot/IGSF5_MOUSE IGSF5_MOUSE]] Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells.<ref>PMID:12773569</ref><ref>PMID:16982697</ref>
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Authors: Akiyoshi, Y., Hamada, D., Goda, N., Tenno, T., Narita, H., Nakagawa, A., Furuse, M., Suzuki, M., Hiroaki, H.
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==About this Structure==
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[[3vqg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VQG OCA].
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Description: Crystal Structure Analysis of the PDZ Domain Derived from the Tight Junction Regulating Protein
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==Reference==
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<references group="xtra"/><references/>
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[[Category: Mus musculus]]
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[[Category: Akiyoshi, Y.]]
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[[Category: Furuse, M.]]
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[[Category: Goda, N.]]
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[[Category: Hamada, D.]]
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[[Category: Hiroaki, H.]]
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[[Category: Nakagawa, A.]]
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[[Category: Narita, H.]]
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[[Category: Suzuki, M.]]
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[[Category: Tenno, T.]]
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[[Category: Pdz domain]]
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[[Category: Peptide binding]]
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[[Category: Peptide binding protein]]

Revision as of 08:53, 27 March 2013

Template:STRUCTURE 3vqg

Contents

Crystal Structure Analysis of the PDZ Domain Derived from the Tight Junction Regulating Protein

Function

[IGSF5_MOUSE] Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells.[1][2]

About this Structure

3vqg is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  1. ↑ Hirabayashi S, Tajima M, Yao I, Nishimura W, Mori H, Hata Y. JAM4, a junctional cell adhesion molecule interacting with a tight junction protein, MAGI-1. Mol Cell Biol. 2003 Jun;23(12):4267-82. PMID:12773569
  2. ↑ Nagamatsu G, Ohmura M, Mizukami T, Hamaguchi I, Hirabayashi S, Yoshida S, Hata Y, Suda T, Ohbo K. A CTX family cell adhesion molecule, JAM4, is expressed in stem cell and progenitor cell populations of both male germ cell and hematopoietic cell lineages. Mol Cell Biol. 2006 Nov;26(22):8498-506. Epub 2006 Sep 18. PMID:16982697 doi:10.1128/MCB.01502-06

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