4dxx

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'''Unreleased structure'''
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{{STRUCTURE_4dxx| PDB=4dxx | SCENE= }}
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===TGT K52M mutant crystallized at pH 8.5===
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The entry 4dxx is ON HOLD until Mar 27 2014
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==Function==
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[[http://www.uniprot.org/uniprot/TGT_ZYMMO TGT_ZYMMO]] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]
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Authors: Jakobi, S., Ritschel, T., Heine, A., Klebe, G.
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==About this Structure==
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[[4dxx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zymomonas_mobilis Zymomonas mobilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DXX OCA].
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Description: TGT K52M mutant crystallized at pH 8.5
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[[Category: Zymomonas mobilis]]
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[[Category: Heine, A.]]
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[[Category: Jakobi, S.]]
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[[Category: Klebe, G.]]
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[[Category: Ritschel, T.]]
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[[Category: Dimer interface]]
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[[Category: Functional dimer]]
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[[Category: Guanine binding]]
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[[Category: Guanine exchange enzyme]]
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[[Category: Transferase]]
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[[Category: Trna binding]]
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[[Category: Zinc binding]]

Revision as of 08:56, 27 March 2013

Template:STRUCTURE 4dxx

TGT K52M mutant crystallized at pH 8.5

Function

[TGT_ZYMMO] Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).[HAMAP-Rule:MF_00168]

About this Structure

4dxx is a 1 chain structure with sequence from Zymomonas mobilis. Full crystallographic information is available from OCA.

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OCA

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