4e52

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'''Unreleased structure'''
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{{STRUCTURE_4e52| PDB=4e52 | SCENE= }}
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===Crystal structure of Haemophilus Eagan 4A polysaccharide bound human lung surfactant protein D===
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{{ABSTRACT_PUBMED_19799916}}
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The entry 4e52 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/SFTPD_HUMAN SFTPD_HUMAN]] Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.
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Authors: Shrive, A.K., Greenhough, T.J.
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==About this Structure==
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[[4e52]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E52 OCA].
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Description: Crystal structure of Haemophilus Eagan 4A polysaccharide bound human lung surfactant protein D
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==Reference==
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<ref group="xtra">PMID:019799916</ref><ref group="xtra">PMID:012888356</ref><references group="xtra"/><references/>
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[[Category: Homo sapiens]]
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[[Category: Greenhough, T J.]]
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[[Category: Shrive, A K.]]
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[[Category: Alpha-helical coiled coil]]
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[[Category: Carbohydrate recognition domain]]
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[[Category: Lectin]]
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[[Category: Neck+crd]]
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[[Category: Sugar binding protein]]
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[[Category: Trimeric recombinant collectin fragment]]

Revision as of 08:57, 27 March 2013

Template:STRUCTURE 4e52

Contents

Crystal structure of Haemophilus Eagan 4A polysaccharide bound human lung surfactant protein D

Template:ABSTRACT PUBMED 19799916

Function

[SFTPD_HUMAN] Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.

About this Structure

4e52 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Shrive AK, Martin C, Burns I, Paterson JM, Martin JD, Townsend JP, Waters P, Clark HW, Kishore U, Reid KB, Greenhough TJ. Structural characterisation of ligand-binding determinants in human lung surfactant protein D: influence of Asp325. J Mol Biol. 2009 Dec 11;394(4):776-88. Epub 2009 Sep 30. PMID:19799916 doi:10.1016/j.jmb.2009.09.057
  • Shrive AK, Tharia HA, Strong P, Kishore U, Burns I, Rizkallah PJ, Reid KB, Greenhough TJ. High-resolution structural insights into ligand binding and immune cell recognition by human lung surfactant protein D. J Mol Biol. 2003 Aug 8;331(2):509-23. PMID:12888356

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OCA

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