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3iob
From Proteopedia
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===Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.80 Ang resolution in complex with 5'-deoxy-5'-thioadenosine=== | ===Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.80 Ang resolution in complex with 5'-deoxy-5'-thioadenosine=== | ||
| + | {{ABSTRACT_PUBMED_19827080}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/PANC_MYCTU PANC_MYCTU]] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.<ref>PMID:11669627</ref> | |
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3iob]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IOB OCA]. | |
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| + | ==See Also== | ||
| + | *[[Pantothenate synthetase|Pantothenate synthetase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:019827080</ref><references group="xtra"/><references/> |
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Pantoate--beta-alanine ligase]] | [[Category: Pantoate--beta-alanine ligase]] | ||
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[[Category: Scott, D E.]] | [[Category: Scott, D E.]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
| - | [[Category: Cytoplasm]] | ||
[[Category: Drug design]] | [[Category: Drug design]] | ||
[[Category: Dynamic combinatorial chemistry]] | [[Category: Dynamic combinatorial chemistry]] | ||
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[[Category: Nucleotide-binding]] | [[Category: Nucleotide-binding]] | ||
[[Category: Pantothenate biosynthesis]] | [[Category: Pantothenate biosynthesis]] | ||
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Revision as of 09:09, 27 March 2013
Contents |
Crystal Structure of Mycobacterium Tuberculosis Pantothenate Synthetase at 1.80 Ang resolution in complex with 5'-deoxy-5'-thioadenosine
Template:ABSTRACT PUBMED 19827080
Function
[PANC_MYCTU] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.[1]
About this Structure
3iob is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
See Also
Reference
- Scott DE, Dawes GJ, Ando M, Abell C, Ciulli A. A fragment-based approach to probing adenosine recognition sites by using dynamic combinatorial chemistry. Chembiochem. 2009 Nov 23;10(17):2772-9. PMID:19827080 doi:10.1002/cbic.200900537
