3jto

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[[Image:3jto.jpg|left|200px]]
 
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{{STRUCTURE_3jto| PDB=3jto | SCENE= }}
{{STRUCTURE_3jto| PDB=3jto | SCENE= }}
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===Crystal structure of the c-terminal domain of YpbH===
===Crystal structure of the c-terminal domain of YpbH===
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{{ABSTRACT_PUBMED_019801546}}
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==Function==
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[[http://www.uniprot.org/uniprot/MECA2_BACSU MECA2_BACSU]] Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Also involved in Spx degradation by ClpC (By similarity). Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation.<ref>PMID:11914365</ref>
==About this Structure==
==About this Structure==
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3JTO is a 6 chains structure of sequences from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTO OCA].
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[[3jto]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTO OCA].
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==Reference==
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<references group="xtra"/><references/>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Mei, Z.]]
[[Category: Mei, Z.]]
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[[Category: Sporulation]]
[[Category: Sporulation]]
[[Category: Ypbh]]
[[Category: Ypbh]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 30 09:32:37 2009''
 

Revision as of 09:11, 27 March 2013

Template:STRUCTURE 3jto

Contents

Crystal structure of the c-terminal domain of YpbH

Template:ABSTRACT PUBMED 019801546

Function

[MECA2_BACSU] Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Also involved in Spx degradation by ClpC (By similarity). Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation.[1]

About this Structure

3jto is a 6 chain structure with sequence from Bacillus subtilis. Full crystallographic information is available from OCA.

Reference

  1. ↑ Persuh M, Mandic-Mulec I, Dubnau D. A MecA paralog, YpbH, binds ClpC, affecting both competence and sporulation. J Bacteriol. 2002 Apr;184(8):2310-3. PMID:11914365

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