This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3it7
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
| - | [[Image:3it7.png|left|200px]] | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3it7", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3it7| PDB=3it7 | SCENE= }} | {{STRUCTURE_3it7| PDB=3it7 | SCENE= }} | ||
| - | |||
===Crystal Structure of the LasA virulence factor from Pseudomonas aeruginosa=== | ===Crystal Structure of the LasA virulence factor from Pseudomonas aeruginosa=== | ||
| + | {{ABSTRACT_PUBMED_20026068}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/LASA_PSEAE LASA_PSEAE]] Involved in proteolysis and elastolysis. Degradation of elastin is likely to contribute to the pathogenicity of P.aeruginosa. | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3it7]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IT7 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020026068</ref><references group="xtra"/><references/> |
| - | [[Category: Pseudomonas aeruginosa | + | [[Category: Pseudomonas aeruginosa]] |
[[Category: Conners, R.]] | [[Category: Conners, R.]] | ||
[[Category: Gamblin, S J.]] | [[Category: Gamblin, S J.]] | ||
| Line 40: | Line 27: | ||
[[Category: Metalloprotease]] | [[Category: Metalloprotease]] | ||
[[Category: Protease]] | [[Category: Protease]] | ||
| - | [[Category: Zinc]] | ||
[[Category: Zymogen]] | [[Category: Zymogen]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 31 12:46:31 2010'' | ||
Revision as of 09:23, 27 March 2013
Contents |
Crystal Structure of the LasA virulence factor from Pseudomonas aeruginosa
Template:ABSTRACT PUBMED 20026068
Function
[LASA_PSEAE] Involved in proteolysis and elastolysis. Degradation of elastin is likely to contribute to the pathogenicity of P.aeruginosa.
About this Structure
3it7 is a 2 chain structure with sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.
Reference
- Spencer J, Murphy LM, Conners R, Sessions RB, Gamblin SJ. Crystal structure of the LasA virulence factor from Pseudomonas aeruginosa: substrate specificity and mechanism of M23 metallopeptidases. J Mol Biol. 2010 Mar 5;396(4):908-23. Epub 2009 Dec 21. PMID:20026068 doi:10.1016/j.jmb.2009.12.021
