3k1x
From Proteopedia
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{{STRUCTURE_3k1x| PDB=3k1x | SCENE= }} | {{STRUCTURE_3k1x| PDB=3k1x | SCENE= }} | ||
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===Acidic Fibroblast Growth Factor (FGF-1) complexed with dobesilate=== | ===Acidic Fibroblast Growth Factor (FGF-1) complexed with dobesilate=== | ||
| + | {{ABSTRACT_PUBMED_20145243}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/FGF1_HUMAN FGF1_HUMAN]] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.<ref>PMID:8663044</ref><ref>PMID:16597617</ref><ref>PMID:20145243</ref> | |
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3k1x]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K1X OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020145243</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Fernandez, I S.]] | [[Category: Fernandez, I S.]] | ||
[[Category: Gimenez-Gallego, G.]] | [[Category: Gimenez-Gallego, G.]] | ||
[[Category: Romero, A.]] | [[Category: Romero, A.]] | ||
| - | [[Category: Acetylation]] | ||
[[Category: Acidic fibroblast growth factor]] | [[Category: Acidic fibroblast growth factor]] | ||
[[Category: Hormone]] | [[Category: Hormone]] | ||
[[Category: Inhibitor]] | [[Category: Inhibitor]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 12 10:34:30 2010'' | ||
Revision as of 09:24, 27 March 2013
Contents |
Acidic Fibroblast Growth Factor (FGF-1) complexed with dobesilate
Template:ABSTRACT PUBMED 20145243
Function
[FGF1_HUMAN] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.[1][2][3]
About this Structure
3k1x is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Fernandez IS, Cuevas P, Angulo J, Lopez-Navajas P, Canales-Mayordomo A, Gonzalez-Corrochano R, Lozano RM, Valverde S, Jimenez-Barbero J, Romero A, Gimenez-Gallego G. Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors. J Biol Chem. 2010 Apr 9;285(15):11714-29. Epub 2010 Feb 9. PMID:20145243 doi:10.1074/jbc.M109.064618
- ↑ Ornitz DM, Xu J, Colvin JS, McEwen DG, MacArthur CA, Coulier F, Gao G, Goldfarb M. Receptor specificity of the fibroblast growth factor family. J Biol Chem. 1996 Jun 21;271(25):15292-7. PMID:8663044
- ↑ Zhang X, Ibrahimi OA, Olsen SK, Umemori H, Mohammadi M, Ornitz DM. Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. J Biol Chem. 2006 Jun 9;281(23):15694-700. Epub 2006 Apr 4. PMID:16597617 doi:10.1074/jbc.M601252200
- ↑ Fernandez IS, Cuevas P, Angulo J, Lopez-Navajas P, Canales-Mayordomo A, Gonzalez-Corrochano R, Lozano RM, Valverde S, Jimenez-Barbero J, Romero A, Gimenez-Gallego G. Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors. J Biol Chem. 2010 Apr 9;285(15):11714-29. Epub 2010 Feb 9. PMID:20145243 doi:10.1074/jbc.M109.064618
