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3iwx

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Revision as of 09:24, 27 March 2013

Template:STRUCTURE 3iwx

Contents

Crystal structure of cisplatin bound to a human copper chaperone (dimer)

Template:ABSTRACT PUBMED 19807176

Function

[ATOX1_HUMAN] Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense.

About this Structure

3iwx is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Boal AK, Rosenzweig AC. Crystal structures of cisplatin bound to a human copper chaperone. J Am Chem Soc. 2009 Oct 14;131(40):14196-7. PMID:19807176 doi:10.1021/ja906363t

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OCA

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