3it5

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{{STRUCTURE_3it5| PDB=3it5 | SCENE= }}
{{STRUCTURE_3it5| PDB=3it5 | SCENE= }}
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===Crystal Structure of the LasA Virulence Factor from Pseudomonas aeruginosa===
===Crystal Structure of the LasA Virulence Factor from Pseudomonas aeruginosa===
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{{ABSTRACT_PUBMED_20026068}}
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==Function==
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[[http://www.uniprot.org/uniprot/LASA_PSEAE LASA_PSEAE]] Involved in proteolysis and elastolysis. Degradation of elastin is likely to contribute to the pathogenicity of P.aeruginosa.
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{{ABSTRACT_PUBMED_20026068}}
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==About this Structure==
==About this Structure==
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3IT5 is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IT5 OCA].
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[[3it5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IT5 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:20026068</ref><references group="xtra"/>
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<ref group="xtra">PMID:020026068</ref><references group="xtra"/><references/>
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[[Category: Pseudomonas aeruginosa pao1]]
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[[Category: Pseudomonas aeruginosa]]
[[Category: Conners, R.]]
[[Category: Conners, R.]]
[[Category: Gamblin, S J.]]
[[Category: Gamblin, S J.]]
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[[Category: Metalloprotease]]
[[Category: Metalloprotease]]
[[Category: Protease]]
[[Category: Protease]]
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[[Category: Zinc]]
 
[[Category: Zymogen]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 31 13:09:47 2010''
 

Revision as of 09:36, 27 March 2013

Template:STRUCTURE 3it5

Contents

Crystal Structure of the LasA Virulence Factor from Pseudomonas aeruginosa

Template:ABSTRACT PUBMED 20026068

Function

[LASA_PSEAE] Involved in proteolysis and elastolysis. Degradation of elastin is likely to contribute to the pathogenicity of P.aeruginosa.

About this Structure

3it5 is a 4 chain structure with sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.

Reference

  • Spencer J, Murphy LM, Conners R, Sessions RB, Gamblin SJ. Crystal structure of the LasA virulence factor from Pseudomonas aeruginosa: substrate specificity and mechanism of M23 metallopeptidases. J Mol Biol. 2010 Mar 5;396(4):908-23. Epub 2009 Dec 21. PMID:20026068 doi:10.1016/j.jmb.2009.12.021

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