3iwv
From Proteopedia
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{{STRUCTURE_3iwv| PDB=3iwv | SCENE= }} | {{STRUCTURE_3iwv| PDB=3iwv | SCENE= }} | ||
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===Crystal structure of Y116T mutant of 5-HYDROXYISOURATE HYDROLASE (TRP)=== | ===Crystal structure of Y116T mutant of 5-HYDROXYISOURATE HYDROLASE (TRP)=== | ||
| + | {{ABSTRACT_PUBMED_16952372}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/HIUH_DANRE HIUH_DANRE]] Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU). | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:016952372</ref><references group="xtra"/> | + | <ref group="xtra">PMID:016952372</ref><references group="xtra"/><references/> |
[[Category: Danio rerio]] | [[Category: Danio rerio]] | ||
[[Category: Hydroxyisourate hydrolase]] | [[Category: Hydroxyisourate hydrolase]] | ||
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[[Category: Ramazzina, I.]] | [[Category: Ramazzina, I.]] | ||
[[Category: Zanotti, G.]] | [[Category: Zanotti, G.]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Molecular evolution]] | ||
| + | [[Category: Peroxisome]] | ||
| + | [[Category: Purine metabolism]] | ||
| + | [[Category: Thyroid hormone]] | ||
| + | [[Category: Transthyretin]] | ||
| + | [[Category: Uric acid degradation]] | ||
Revision as of 09:40, 27 March 2013
Contents |
Crystal structure of Y116T mutant of 5-HYDROXYISOURATE HYDROLASE (TRP)
Template:ABSTRACT PUBMED 16952372
Function
[HIUH_DANRE] Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).
About this Structure
3iwv is a 4 chain structure with sequence from Danio rerio. Full crystallographic information is available from OCA.
Reference
- Zanotti G, Cendron L, Ramazzina I, Folli C, Percudani R, Berni R. Structure of zebra fish HIUase: insights into evolution of an enzyme to a hormone transporter. J Mol Biol. 2006 Oct 13;363(1):1-9. Epub 2006 Aug 2. PMID:16952372 doi:10.1016/j.jmb.2006.07.079
