3iv5
From Proteopedia
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{{STRUCTURE_3iv5| PDB=3iv5 | SCENE= }} | {{STRUCTURE_3iv5| PDB=3iv5 | SCENE= }} | ||
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===Crystal structure of Fis bound to 27 bp optimal binding sequence F1=== | ===Crystal structure of Fis bound to 27 bp optimal binding sequence F1=== | ||
| + | {{ABSTRACT_PUBMED_20395367}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/FIS_ECOLI FIS_ECOLI]] Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin-mediated DNA inversion. Prevents initiation of DNA replication from oriC.<ref>PMID:2209559</ref><ref>PMID:8836178</ref> | |
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3iv5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3IV5 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020395367</ref><references group="xtra"/><references/> |
| - | [[Category: Escherichia coli | + | [[Category: Escherichia coli]] |
[[Category: Cascio, D.]] | [[Category: Cascio, D.]] | ||
[[Category: Johnson, R C.]] | [[Category: Johnson, R C.]] | ||
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[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
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Revision as of 09:44, 27 March 2013
Contents |
Crystal structure of Fis bound to 27 bp optimal binding sequence F1
Template:ABSTRACT PUBMED 20395367
Function
[FIS_ECOLI] Activates ribosomal RNA transcription, as well other genes. Plays a direct role in upstream activation of rRNA promoters. Binds to a recombinational enhancer sequence that is required to stimulate hin-mediated DNA inversion. Prevents initiation of DNA replication from oriC.[1][2]
About this Structure
3iv5 is a 4 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
- Stella S, Cascio D, Johnson RC. The shape of the DNA minor groove directs binding by the DNA-bending protein Fis. Genes Dev. 2010 Apr 15;24(8):814-26. PMID:20395367 doi:24/8/814
- ↑ Ross W, Thompson JF, Newlands JT, Gourse RL. E.coli Fis protein activates ribosomal RNA transcription in vitro and in vivo. EMBO J. 1990 Nov;9(11):3733-42. PMID:2209559
- ↑ Wold S, Crooke E, Skarstad K. The Escherichia coli Fis protein prevents initiation of DNA replication from oriC in vitro. Nucleic Acids Res. 1996 Sep 15;24(18):3527-32. PMID:8836178
