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3jub
From Proteopedia
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{{STRUCTURE_3jub| PDB=3jub | SCENE= }} | {{STRUCTURE_3jub| PDB=3jub | SCENE= }} | ||
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===Human gamma-glutamylamine cyclotransferase=== | ===Human gamma-glutamylamine cyclotransferase=== | ||
| + | {{ABSTRACT_PUBMED_20110353}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/A2LD1_HUMAN A2LD1_HUMAN]] Contributes to degradation of proteins cross-linked by transglutaminases. Degrades the cross-link between a lysine and a glutamic acid residue from two proteins that have been cross-linked by transglutaminases. Catalyzes the formation of 5-oxoproline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma-glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine. | |
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3jub]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JUB OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020110353</ref><references group="xtra"/><references/> |
[[Category: Gamma-glutamylcyclotransferase]] | [[Category: Gamma-glutamylcyclotransferase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: Oxoproline]] | [[Category: Oxoproline]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 31 13:14:29 2010'' | ||
Revision as of 09:45, 27 March 2013
Contents |
Human gamma-glutamylamine cyclotransferase
Template:ABSTRACT PUBMED 20110353
Function
[A2LD1_HUMAN] Contributes to degradation of proteins cross-linked by transglutaminases. Degrades the cross-link between a lysine and a glutamic acid residue from two proteins that have been cross-linked by transglutaminases. Catalyzes the formation of 5-oxoproline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma-glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine.
About this Structure
3jub is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Oakley AJ, Coggan M, Board PG. Identification and characterization of gamma-glutamylamine cyclotransferase, an enzyme responsible for gamma-glutamyl-epsilon-lysine catabolism. J Biol Chem. 2010 Mar 26;285(13):9642-8. Epub 2010 Jan 28. PMID:20110353 doi:10.1074/jbc.M109.082099
