Acetylxylan esterase
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| - | '''Acetylxylan esterase''' (AXE) catalyzes the deacetylation of xylans and xylo-oligosaccharides. AXE is involved in the biodegradation of hemicellulose. AXE hydrolyzes the ester linkages of the acetyl groups in position 2 and/or 3 of xylose moiety of naturally acetylated xylan from hardwood. AXE is one of the accessory enzymes which are part of the xylanolytic system. Together with xylanase, β-xylosidase, | + | '''Acetylxylan esterase''' (AXE) catalyzes the deacetylation of xylans and xylo-oligosaccharides. AXE is involved in the biodegradation of hemicellulose. AXE hydrolyzes the ester linkages of the acetyl groups in position 2 and/or 3 of xylose moiety of naturally acetylated xylan from hardwood. AXE is one of the accessory enzymes which are part of the xylanolytic system. Together with xylanase, β-xylosidase, α-arabinofuranosidase and methylglucoronidase, AXE is required for the complete degradation of xylan. Xylan is the major constituent of hemicellulose which is the second most abundant polysaccharide in plants. |
==3D structures of acetylxylan esterase== | ==3D structures of acetylxylan esterase== | ||
Revision as of 09:15, 3 April 2013
Acetylxylan esterase (AXE) catalyzes the deacetylation of xylans and xylo-oligosaccharides. AXE is involved in the biodegradation of hemicellulose. AXE hydrolyzes the ester linkages of the acetyl groups in position 2 and/or 3 of xylose moiety of naturally acetylated xylan from hardwood. AXE is one of the accessory enzymes which are part of the xylanolytic system. Together with xylanase, β-xylosidase, α-arabinofuranosidase and methylglucoronidase, AXE is required for the complete degradation of xylan. Xylan is the major constituent of hemicellulose which is the second most abundant polysaccharide in plants.
3D structures of acetylxylan esterase
Updated on 03-April-2013
1bs9, 2axe – PpAXE – Penicillium purpurogenum
1g66 – PpAXE II
1qoz – AXE catalytic domain – Trichoderma reesei
1vlq, 3m81 – TmAXE – Thermotoga maritima
3fvr, 3fvt, 2xlb – BpAXE – Bacillus pumilus
Acetylxylan esterase binary complex
2c71, 2c79 – AXE + metal ion – Clostridium thermocellum
3fyt – BpAXE (mutant) + β-D-xylopyranose
3fyu – BpAXE + D-xylose
2xlc – BpAXE + diethyl phosphonate
3m83 – TmAXE + paraoxon inhibitor
3m82 – TmAXE + PMSF inhibitor
