3v62
From Proteopedia
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{{STRUCTURE_3v62| PDB=3v62 | SCENE= }} | {{STRUCTURE_3v62| PDB=3v62 | SCENE= }} | ||
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===Structure of the S. cerevisiae Srs2 C-terminal domain in complex with PCNA conjugated to SUMO on lysine 164=== | ===Structure of the S. cerevisiae Srs2 C-terminal domain in complex with PCNA conjugated to SUMO on lysine 164=== | ||
| + | {{ABSTRACT_PUBMED_22382979}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/SMT3_YEAST SMT3_YEAST]] Not known; suppressor of MIF2 mutations. [[http://www.uniprot.org/uniprot/SRS2_YEAST SRS2_YEAST]] ATP-dependent DNA helicase involved in DNA repair at least for UV-induced lesions. The polarity of the helicase activity was determined to be 3' to 5'. [[http://www.uniprot.org/uniprot/PCNA_YEAST PCNA_YEAST]] This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Involved in DNA repair.<ref>PMID:11545742</ref> <ref>PMID:12226657</ref> | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3v62]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[3v62]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V62 OCA]. |
==See Also== | ==See Also== | ||
*[[Proliferating Cell Nuclear Antigen|Proliferating Cell Nuclear Antigen]] | *[[Proliferating Cell Nuclear Antigen|Proliferating Cell Nuclear Antigen]] | ||
*[[SUMO|SUMO]] | *[[SUMO|SUMO]] | ||
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| + | ==Reference== | ||
| + | <references group="xtra"/><references/> | ||
[[Category: DNA helicase]] | [[Category: DNA helicase]] | ||
| - | [[Category: Saccharomyces cerevisiae]] | + | [[Category: Saccharomyces cerevisiae s288c]] |
[[Category: Armstrong, A A.]] | [[Category: Armstrong, A A.]] | ||
[[Category: Lima, C D.]] | [[Category: Lima, C D.]] | ||
Revision as of 23:56, 3 April 2013
Contents |
Structure of the S. cerevisiae Srs2 C-terminal domain in complex with PCNA conjugated to SUMO on lysine 164
Template:ABSTRACT PUBMED 22382979
Function
[SMT3_YEAST] Not known; suppressor of MIF2 mutations. [SRS2_YEAST] ATP-dependent DNA helicase involved in DNA repair at least for UV-induced lesions. The polarity of the helicase activity was determined to be 3' to 5'. [PCNA_YEAST] This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Involved in DNA repair.[1] [2]
About this Structure
3v62 is a 6 chain structure with sequence from Saccharomyces cerevisiae s288c. Full crystallographic information is available from OCA.
See Also
Reference
- ↑ Haracska L, Kondratick CM, Unk I, Prakash S, Prakash L. Interaction with PCNA is essential for yeast DNA polymerase eta function. Mol Cell. 2001 Aug;8(2):407-15. PMID:11545742
- ↑ Hoege C, Pfander B, Moldovan GL, Pyrowolakis G, Jentsch S. RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. Nature. 2002 Sep 12;419(6903):135-41. PMID:12226657 doi:10.1038/nature00991
Categories: DNA helicase | Saccharomyces cerevisiae s288c | Armstrong, A A. | Lima, C D. | Mohideen, F. | Nem modification on pcna cys22 and cys81 reductive methylation of all lysine residues on smt3 | Nuclear | Post-translational modification dna replication dna damage response | Protein binding-dna binding protein complex | Srs2 | Ubiquitin-like protein pcna
