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4is2

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Revision as of 01:51, 4 April 2013

Template:STRUCTURE 4is2

Crystal structure of the apo form of a 3alpha-hydroxysteroid dehydrogenase (BaiA2) associated with secondary bile acid synthesis from Clostridium scindens VPI12708 at 1.90 A resolution

Function

[BAIA2_EUBSP] 7-alpha-dehydroxylation of cholic acid and chenodeoxycholate, yielding deoxycholic acid and lithocholic acid, respectively. Highest affinity with taurochenodeoxycholic acid.

About this Structure

4is2 is a 1 chain structure with sequence from Clostridium scindens. Full crystallographic information is available from OCA.

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