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3kf2

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Template:STRUCTURE 3kf2

The HCV NS3/NS4A protease apo structure

About this Structure

3kf2 is a 4 chain structure with sequence from Hepatitis c virus. Full crystallographic information is available from OCA.

Reference

  • Cummings MD, Lindberg J, Lin TI, de Kock H, Lenz O, Lilja E, Fellander S, Baraznenok V, Nystrom S, Nilsson M, Vrang L, Edlund M, Rosenquist A, Samuelsson B, Raboisson P, Simmen K. Induced-fit binding of the macrocyclic noncovalent inhibitor TMC435 to its HCV NS3/NS4A protease target. Angew Chem Int Ed Engl. 2010 Feb 22;49(9):1652-5. PMID:20166108 doi:10.1002/anie.200906696

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OCA

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