3kot

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[[Image:3kot.png|left|200px]]
 
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{{STRUCTURE_3kot| PDB=3kot | SCENE= }}
{{STRUCTURE_3kot| PDB=3kot | SCENE= }}
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===Structure of the Citrobacter freundii effector binding domain containing three amino acid substitutions: T103V, S221A and Y264F===
===Structure of the Citrobacter freundii effector binding domain containing three amino acid substitutions: T103V, S221A and Y264F===
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{{ABSTRACT_PUBMED_20594961}}
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==Function==
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[[http://www.uniprot.org/uniprot/AMPR_CITFR AMPR_CITFR]] Regulates the expression of the beta-lactamase gene. Represses cephalosporinase (AmpC) in the presence of beta-lactams and induces it in the absence of them.
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{{ABSTRACT_PUBMED_20594961}}
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==About this Structure==
==About this Structure==
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3KOT is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Citrobacter_freundii Citrobacter freundii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOT OCA].
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[[3kot]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Citrobacter_freundii Citrobacter freundii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KOT OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:20594961</ref><references group="xtra"/>
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<ref group="xtra">PMID:020594961</ref><references group="xtra"/><references/>
[[Category: Citrobacter freundii]]
[[Category: Citrobacter freundii]]
[[Category: Balcewich, M D.]]
[[Category: Balcewich, M D.]]
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[[Category: Transcription]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 28 12:00:08 2010''
 

Revision as of 02:21, 4 April 2013

Template:STRUCTURE 3kot

Contents

Structure of the Citrobacter freundii effector binding domain containing three amino acid substitutions: T103V, S221A and Y264F

Template:ABSTRACT PUBMED 20594961

Function

[AMPR_CITFR] Regulates the expression of the beta-lactamase gene. Represses cephalosporinase (AmpC) in the presence of beta-lactams and induces it in the absence of them.

About this Structure

3kot is a 1 chain structure with sequence from Citrobacter freundii. Full crystallographic information is available from OCA.

Reference

  • Balcewich MD, Reeve TM, Orlikow EA, Donald LJ, Vocadlo DJ, Mark BL. Crystal structure of the AmpR effector binding domain provides insight into the molecular regulation of inducible ampc beta-lactamase. J Mol Biol. 2010 Jul 30;400(5):998-1010. Epub 2010 May 31. PMID:20594961 doi:10.1016/j.jmb.2010.05.040

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OCA

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