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3k2z

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Template:STRUCTURE 3k2z

Crystal structure of a LexA protein from Thermotoga maritima

Function

[LEXA_THEMA] Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity).

About this Structure

3k2z is a 2 chain structure with sequence from Thermotoga maritima. Full crystallographic information is available from OCA.

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OCA

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