3kgg
From Proteopedia
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===X-ray structure of perdeuterated diisopropyl fluorophosphatase (DFPase): Perdeuteration of proteins for neutron diffraction=== | ===X-ray structure of perdeuterated diisopropyl fluorophosphatase (DFPase): Perdeuteration of proteins for neutron diffraction=== | ||
+ | {{ABSTRACT_PUBMED_20383004}} | ||
- | + | ==Function== | |
- | + | [[http://www.uniprot.org/uniprot/DFPA_LOLVU DFPA_LOLVU]] Biological function and substrate unknown. However, it is capable of acting on phosphorus anhydride bonds (such as phosphorus-halide and phosphorus-cyanide) in organophosphorus compounds (including nerve gases).<ref>PMID:15966726</ref> | |
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==About this Structure== | ==About this Structure== | ||
- | + | [[3kgg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Loligo_vulgaris Loligo vulgaris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KGG OCA]. | |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020383004</ref><references group="xtra"/><references/> |
[[Category: Diisopropyl-fluorophosphatase]] | [[Category: Diisopropyl-fluorophosphatase]] | ||
[[Category: Loligo vulgaris]] | [[Category: Loligo vulgaris]] | ||
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[[Category: Terjans, H R.]] | [[Category: Terjans, H R.]] | ||
[[Category: Beta propeller]] | [[Category: Beta propeller]] | ||
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[[Category: Hydrolase]] | [[Category: Hydrolase]] | ||
[[Category: Metal-binding]] | [[Category: Metal-binding]] | ||
[[Category: Phosphotriesterase]] | [[Category: Phosphotriesterase]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 28 10:53:50 2010'' |
Revision as of 02:42, 4 April 2013
Contents |
X-ray structure of perdeuterated diisopropyl fluorophosphatase (DFPase): Perdeuteration of proteins for neutron diffraction
Template:ABSTRACT PUBMED 20383004
Function
[DFPA_LOLVU] Biological function and substrate unknown. However, it is capable of acting on phosphorus anhydride bonds (such as phosphorus-halide and phosphorus-cyanide) in organophosphorus compounds (including nerve gases).[1]
About this Structure
3kgg is a 1 chain structure with sequence from Loligo vulgaris. Full crystallographic information is available from OCA.
Reference
- Blum MM, Tomanicek SJ, John H, Hanson BL, Ruterjans H, Schoenborn BP, Langan P, Chen JC. X-ray structure of perdeuterated diisopropyl fluorophosphatase (DFPase): perdeuteration of proteins for neutron diffraction. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Apr 1;66(Pt, 4):379-85. Epub 2010 Mar 26. PMID:20383004 doi:10.1107/S1744309110004318
- ↑ Katsemi V, Lucke C, Koepke J, Lohr F, Maurer S, Fritzsch G, Ruterjans H. Mutational and structural studies of the diisopropylfluorophosphatase from Loligo vulgaris shed new light on the catalytic mechanism of the enzyme. Biochemistry. 2005 Jun 28;44(25):9022-33. PMID:15966726 doi:10.1021/bi0500675