3kjm

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[[Image:3kjm.png|left|200px]]
 
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{{STRUCTURE_3kjm| PDB=3kjm | SCENE= }}
{{STRUCTURE_3kjm| PDB=3kjm | SCENE= }}
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===Leu492Ala mutant of Maize cytokinin oxidase/dehydrogenase complexed with phenylurea inhibitor CPPU===
===Leu492Ala mutant of Maize cytokinin oxidase/dehydrogenase complexed with phenylurea inhibitor CPPU===
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{{ABSTRACT_PUBMED_20478354}}
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==Function==
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[[http://www.uniprot.org/uniprot/CKX1_MAIZE CKX1_MAIZE]] Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives that are plant hormones, where the substituent is an isopentenyl group. Cleaves zeatin, isopentenyladenine, isopentenyladenosine, zeatin riboside and cis-zeatin, but not dihydrozeatin, kinetin and benzylaminopurine.
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{{ABSTRACT_PUBMED_20478354}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:020478354</ref><references group="xtra"/>
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<ref group="xtra">PMID:020478354</ref><references group="xtra"/><references/>
[[Category: Cytokinin dehydrogenase]]
[[Category: Cytokinin dehydrogenase]]
[[Category: Zea mays]]
[[Category: Zea mays]]
[[Category: Briozzo, P.]]
[[Category: Briozzo, P.]]
[[Category: Kopecny, D.]]
[[Category: Kopecny, D.]]
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[[Category: Cytokinin oxidase/dehydrogenase]]
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[[Category: Fad]]
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[[Category: Flavoprotein]]
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[[Category: Glycoprotein]]
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[[Category: Inhibitor]]
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[[Category: Oxidoreductase-inhibitor complex]]
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[[Category: Secreted]]

Revision as of 02:42, 4 April 2013

Template:STRUCTURE 3kjm

Contents

Leu492Ala mutant of Maize cytokinin oxidase/dehydrogenase complexed with phenylurea inhibitor CPPU

Template:ABSTRACT PUBMED 20478354

Function

[CKX1_MAIZE] Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives that are plant hormones, where the substituent is an isopentenyl group. Cleaves zeatin, isopentenyladenine, isopentenyladenosine, zeatin riboside and cis-zeatin, but not dihydrozeatin, kinetin and benzylaminopurine.

About this Structure

3kjm is a 1 chain structure with sequence from Zea mays. Full crystallographic information is available from OCA.

Reference

  • Kopecny D, Briozzo P, Popelkova H, Sebela M, Koncitikova R, Spichal L, Nisler J, Madzak C, Frebort I, Laloue M, Houba-Herin N. Phenyl- and benzylurea cytokinins as competitive inhibitors of cytokinin oxidase/dehydrogenase: a structural study. Biochimie. 2010 Aug;92(8):1052-62. Epub 2010 May 15. PMID:20478354 doi:10.1016/j.biochi.2010.05.006

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