3knx
From Proteopedia
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m (Protected "3knx" [edit=sysop:move=sysop]) |
Revision as of 02:48, 4 April 2013
HCV NS3 protease domain with P1-P3 macrocyclic ketoamide inhibitor
Template:ABSTRACT PUBMED 19102654
About this Structure
3knx is a 4 chain structure with sequence from Hepatitis c virus subtype 1a. Full crystallographic information is available from OCA.
Reference
- Venkatraman S, Velazquez F, Wu W, Blackman M, Chen KX, Bogen S, Nair L, Tong X, Chase R, Hart A, Agrawal S, Pichardo J, Prongay A, Cheng KC, Girijavallabhan V, Piwinski J, Shih NY, Njoroge FG. Discovery and structure-activity relationship of P1-P3 ketoamide derived macrocyclic inhibitors of hepatitis C virus NS3 protease. J Med Chem. 2009 Jan 22;52(2):336-46. PMID:19102654 doi:10.1021/jm800940u
Categories: Hepatitis c virus subtype 1a | Agrawal, S. | Blackman, M. | Bogen, S. | Chase, R. | Chen, K X. | Cheng, K C. | Girijavallabhan, V. | Hart, A. | Nair, L. | Njoroge, F G. | Pichardo, J. | Piwinski, J. | Prongay, A. | Shih, N Y. | Tong, X. | Velazquez, F. | Venkatraman, S. | Wu, W. | Atp-binding | Envelope protein | Helicase | Hepatitis c virus | Hydrolase | Macrocyclic ketoamide inhibitor | Membrane | Ns3 protease domain | Nucleotide-binding | Rna replication | Serine protease | Transmembrane | Viral protein
