3kup
From Proteopedia
m (Protected "3kup" [edit=sysop:move=sysop]) |
Revision as of 20:01, 4 April 2013
Crystal Structure of the CBX3 Chromo Shadow Domain
Function
[CBX3_HUMAN] Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
About this Structure
3kup is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Categories: Homo sapiens | Arrowsmith, C H. | Bochkarev, A. | Bountra, C. | Edwards, A M. | Kozieradzki, I. | Li, Y. | Li, Z. | Min, J. | Ouyang, H. | SGC, Structural Genomics Consortium. | Tempel, W. | Weigelt, J. | Chromatin regulator | Chromo shadow domain | Nucleus | Phosphoprotein | Repressor | Sgc | Structural genomics consortium | Transcription | Transcription regulation
