3kxt

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[[Image:3kxt.png|left|200px]]
 
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{{STRUCTURE_3kxt| PDB=3kxt | SCENE= }}
{{STRUCTURE_3kxt| PDB=3kxt | SCENE= }}
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===Crystal structure of Sulfolobus Cren7-dsDNA complex===
===Crystal structure of Sulfolobus Cren7-dsDNA complex===
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{{ABSTRACT_PUBMED_20512977}}
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==Function==
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[[http://www.uniprot.org/uniprot/CREN7_SULSO CREN7_SULSO]] A highly abundant probable chromatin protein, it binds double-strand DNA without sequence specificity; there is approximately 1 Cren7 molecule for 12 bp of DNA. Constrains negative DNA supercoils, increases DNA stability against thermal denaturation. Binding does not require protein methylation. Binds single-strand DNA weakly.<ref>PMID:18096617</ref>
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{{ABSTRACT_PUBMED_20512977}}
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==About this Structure==
==About this Structure==
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3KXT is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KXT OCA].
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[[3kxt]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KXT OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:20512977</ref><references group="xtra"/>
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<ref group="xtra">PMID:020512977</ref><references group="xtra"/><references/>
[[Category: Sulfolobus solfataricus]]
[[Category: Sulfolobus solfataricus]]
[[Category: Feng, Y.]]
[[Category: Feng, Y.]]
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[[Category: Minor-groove binding]]
[[Category: Minor-groove binding]]
[[Category: Protein-dna complex]]
[[Category: Protein-dna complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 16 08:10:22 2010''
 

Revision as of 20:03, 4 April 2013

Template:STRUCTURE 3kxt

Contents

Crystal structure of Sulfolobus Cren7-dsDNA complex

Template:ABSTRACT PUBMED 20512977

Function

[CREN7_SULSO] A highly abundant probable chromatin protein, it binds double-strand DNA without sequence specificity; there is approximately 1 Cren7 molecule for 12 bp of DNA. Constrains negative DNA supercoils, increases DNA stability against thermal denaturation. Binding does not require protein methylation. Binds single-strand DNA weakly.[1]

About this Structure

3kxt is a 3 chain structure with sequence from Sulfolobus solfataricus. Full crystallographic information is available from OCA.

Reference

  • Feng Y, Yao H, Wang J. Crystal structure of the crenarchaeal conserved chromatin protein Cren7 and double-stranded DNA complex. Protein Sci. 2010 Jun;19(6):1253-7. PMID:20512977 doi:10.1002/pro.385
  1. ↑ Guo L, Feng Y, Zhang Z, Yao H, Luo Y, Wang J, Huang L. Biochemical and structural characterization of Cren7, a novel chromatin protein conserved among Crenarchaea. Nucleic Acids Res. 2008 Mar;36(4):1129-37. Epub 2007 Dec 20. PMID:18096617 doi:10.1093/nar/gkm1128

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