3lhc

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{{STRUCTURE_3lhc| PDB=3lhc | SCENE= }}
{{STRUCTURE_3lhc| PDB=3lhc | SCENE= }}
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===Crystal structure of cyanovirin-n swapping domain b mutant===
===Crystal structure of cyanovirin-n swapping domain b mutant===
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{{ABSTRACT_PUBMED_20147291}}
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==Function==
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[[http://www.uniprot.org/uniprot/CVN_NOSEL CVN_NOSEL]] Mannose-binding lectin.<ref>PMID:9210678</ref> <ref>PMID:12678493</ref>
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{{ABSTRACT_PUBMED_20147291}}
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==About this Structure==
==About this Structure==
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3LHC is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nostoc_ellipsosporum Nostoc ellipsosporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LHC OCA].
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[[3lhc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nostoc_ellipsosporum Nostoc ellipsosporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LHC OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:20147291</ref><references group="xtra"/>
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<ref group="xtra">PMID:020147291</ref><references group="xtra"/><references/>
[[Category: Nostoc ellipsosporum]]
[[Category: Nostoc ellipsosporum]]
[[Category: Aiken, C.]]
[[Category: Aiken, C.]]
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[[Category: Protein synthesis inhibitor]]
[[Category: Protein synthesis inhibitor]]
[[Category: Sugar binding protein]]
[[Category: Sugar binding protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 5 11:23:50 2010''
 

Revision as of 20:14, 4 April 2013

Template:STRUCTURE 3lhc

Contents

Crystal structure of cyanovirin-n swapping domain b mutant

Template:ABSTRACT PUBMED 20147291

Function

[CVN_NOSEL] Mannose-binding lectin.[1] [2]

About this Structure

3lhc is a 1 chain structure with sequence from Nostoc ellipsosporum. Full crystallographic information is available from OCA.

Reference

  • Matei E, Zheng A, Furey W, Rose J, Aiken C, Gronenborn AM. Anti-HIV activity of defective cyanovirin-N mutants is restored by dimerization. J Biol Chem. 2010 Apr 23;285(17):13057-65. Epub 2010 Feb 10. PMID:20147291 doi:10.1074/jbc.M109.094938
  1. ↑ Boyd MR, Gustafson KR, McMahon JB, Shoemaker RH, O'Keefe BR, Mori T, Gulakowski RJ, Wu L, Rivera MI, Laurencot CM, Currens MJ, Cardellina JH 2nd, Buckheit RW Jr, Nara PL, Pannell LK, Sowder RC 2nd, Henderson LE. Discovery of cyanovirin-N, a novel human immunodeficiency virus-inactivating protein that binds viral surface envelope glycoprotein gp120: potential applications to microbicide development. Antimicrob Agents Chemother. 1997 Jul;41(7):1521-30. PMID:9210678
  2. ↑ Botos I, Wlodawer A. Cyanovirin-N: a sugar-binding antiviral protein with a new twist. Cell Mol Life Sci. 2003 Feb;60(2):277-87. PMID:12678493

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