3lkm

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Revision as of 20:20, 4 April 2013

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Template:STRUCTURE 3lkm

Contents 1 1.6 Angstrom Crystal Structure of the Alpha-kinase Domain of Myosin Heavy Chain Kinase A Complex with AMP 2 Function 3 About this Structure 4 Reference

1.6 Angstrom Crystal Structure of the Alpha-kinase Domain of Myosin Heavy Chain Kinase A Complex with AMP

Template:ABSTRACT PUBMED 20197546

Function

[MHCKA_DICDI] Phosphorylates threonine in the C-terminal tail region of myosin II heavy chain. This phosphorylation is critical in regulating the assembly and disassembly of myosin II filament. Requires autophosphorylation for activity.

About this Structure

3lkm is a 1 chain structure with sequence from Dictyostelium discoideum. Full crystallographic information is available from OCA.

Reference

• Ye Q, Crawley SW, Yang Y, Cote GP, Jia Z. Crystal structure of the alpha-kinase domain of Dictyostelium myosin heavy chain kinase A. Sci Signal. 2010 Mar 2;3(111):ra17. PMID:20197546 doi:3/111/ra17