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3l51

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[[Image:3l51.png|left|200px]]
 
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{{STRUCTURE_3l51| PDB=3l51 | SCENE= }}
{{STRUCTURE_3l51| PDB=3l51 | SCENE= }}
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===Crystal Structure of the Mouse Condensin Hinge Domain===
===Crystal Structure of the Mouse Condensin Hinge Domain===
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{{ABSTRACT_PUBMED_20139420}}
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==Function==
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[[http://www.uniprot.org/uniprot/SMC2_MOUSE SMC2_MOUSE]] Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity). [[http://www.uniprot.org/uniprot/SMC4_MOUSE SMC4_MOUSE]] Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity).
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{{ABSTRACT_PUBMED_20139420}}
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==About this Structure==
==About this Structure==
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3L51 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L51 OCA].
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[[3l51]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L51 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:20139420</ref><references group="xtra"/>
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<ref group="xtra">PMID:020139420</ref><references group="xtra"/><references/>
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Griese, J J.]]
[[Category: Griese, J J.]]
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[[Category: Cell cycle]]
[[Category: Cell cycle]]
[[Category: Cell division]]
[[Category: Cell division]]
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[[Category: Cytoplasm]]
 
[[Category: Dna condensation]]
[[Category: Dna condensation]]
[[Category: Hinge domain]]
[[Category: Hinge domain]]
[[Category: Mitosis]]
[[Category: Mitosis]]
[[Category: Nucleus]]
[[Category: Nucleus]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 25 09:41:16 2010''
 

Revision as of 20:28, 4 April 2013

Template:STRUCTURE 3l51

Contents

Crystal Structure of the Mouse Condensin Hinge Domain

Template:ABSTRACT PUBMED 20139420

Function

[SMC2_MOUSE] Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity). [SMC4_MOUSE] Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity).

About this Structure

3l51 is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Griese JJ, Witte G, Hopfner KP. Structure and DNA binding activity of the mouse condensin hinge domain highlight common and diverse features of SMC proteins. Nucleic Acids Res. 2010 Jun;38(10):3454-65. Epub 2010 Feb 5. PMID:20139420 doi:10.1093/nar/gkq038

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