This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3l51

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "3l51" [edit=sysop:move=sysop])

Revision as of 20:28, 4 April 2013

Template:STRUCTURE 3l51

Contents

Crystal Structure of the Mouse Condensin Hinge Domain

Template:ABSTRACT PUBMED 20139420

Function

[SMC2_MOUSE] Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity). [SMC4_MOUSE] Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity).

About this Structure

3l51 is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Griese JJ, Witte G, Hopfner KP. Structure and DNA binding activity of the mouse condensin hinge domain highlight common and diverse features of SMC proteins. Nucleic Acids Res. 2010 Jun;38(10):3454-65. Epub 2010 Feb 5. PMID:20139420 doi:10.1093/nar/gkq038

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3l51"
Personal tools