3l8g

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[[Image:3l8g.png|left|200px]]
 
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{{STRUCTURE_3l8g| PDB=3l8g | SCENE= }}
{{STRUCTURE_3l8g| PDB=3l8g | SCENE= }}
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===Crystal Structure of D,D-heptose 1.7-bisphosphate phosphatase from E. Coli complexed with D-glycero-D-manno-heptose 1 ,7-bisphosphate===
===Crystal Structure of D,D-heptose 1.7-bisphosphate phosphatase from E. Coli complexed with D-glycero-D-manno-heptose 1 ,7-bisphosphate===
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{{ABSTRACT_PUBMED_20050614}}
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==Function==
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[[http://www.uniprot.org/uniprot/GMHB_ECOLI GMHB_ECOLI]] Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate (HBP) by removing the phosphate group at the C-7 position. Also catalyzes the dephosphorylation of fructose-1,6-bisphosphate (Fru1,6bisP).<ref>PMID:11751812</ref> <ref>PMID:16990279</ref>
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{{ABSTRACT_PUBMED_20050614}}
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==About this Structure==
==About this Structure==
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3L8G is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L8G OCA].
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[[3l8g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L8G OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:20050614</ref><references group="xtra"/>
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<ref group="xtra">PMID:020050614</ref><references group="xtra"/><references/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Allen, K N.]]
[[Category: Allen, K N.]]
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[[Category: 7-bisphosphate phosphatase]]
[[Category: 7-bisphosphate phosphatase]]
[[Category: Carbohydrate metabolism]]
[[Category: Carbohydrate metabolism]]
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[[Category: Cytoplasm]]
 
[[Category: D-glycero-d-manno-heptose-1]]
[[Category: D-glycero-d-manno-heptose-1]]
[[Category: Gmhb]]
[[Category: Gmhb]]
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[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Lipopolysaccharide biosynthesis]]
[[Category: Lipopolysaccharide biosynthesis]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 25 09:32:23 2010''
 

Revision as of 20:43, 4 April 2013

Template:STRUCTURE 3l8g

Contents

Crystal Structure of D,D-heptose 1.7-bisphosphate phosphatase from E. Coli complexed with D-glycero-D-manno-heptose 1 ,7-bisphosphate

Template:ABSTRACT PUBMED 20050614

Function

[GMHB_ECOLI] Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate (HBP) by removing the phosphate group at the C-7 position. Also catalyzes the dephosphorylation of fructose-1,6-bisphosphate (Fru1,6bisP).[1] [2]

About this Structure

3l8g is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  • Nguyen HH, Wang L, Huang H, Peisach E, Dunaway-Mariano D, Allen KN. Structural Determinants of Substrate Recognition in the HAD Superfamily Member d-glycero-d-manno-Heptose-1,7-bisphosphate Phosphatase (GmhB) . Biochemistry. 2010 Jan 22. PMID:20050614 doi:10.1021/bi902019q
  1. ↑ Kneidinger B, Marolda C, Graninger M, Zamyatina A, McArthur F, Kosma P, Valvano MA, Messner P. Biosynthesis pathway of ADP-L-glycero-beta-D-manno-heptose in Escherichia coli. J Bacteriol. 2002 Jan;184(2):363-9. PMID:11751812
  2. ↑ Kuznetsova E, Proudfoot M, Gonzalez CF, Brown G, Omelchenko MV, Borozan I, Carmel L, Wolf YI, Mori H, Savchenko AV, Arrowsmith CH, Koonin EV, Edwards AM, Yakunin AF. Genome-wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family. J Biol Chem. 2006 Nov 24;281(47):36149-61. Epub 2006 Sep 21. PMID:16990279 doi:10.1074/jbc.M605449200

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