3zvf
From Proteopedia
| Line 1: | Line 1: | ||
| - | [[Image:3zvf.png|left|200px]] | ||
| - | |||
{{STRUCTURE_3zvf| PDB=3zvf | SCENE= }} | {{STRUCTURE_3zvf| PDB=3zvf | SCENE= }} | ||
| - | |||
===3C protease of Enterovirus 68 complexed with Michael receptor inhibitor 85=== | ===3C protease of Enterovirus 68 complexed with Michael receptor inhibitor 85=== | ||
| + | {{ABSTRACT_PUBMED_23388726}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/A1E4A3_9ENTO A1E4A3_9ENTO]] Protein 2C associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity).[SAAS:SAAS000199_004_016611] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266] RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047] | ||
==About this Structure== | ==About this Structure== | ||
Revision as of 21:38, 10 April 2013
3C protease of Enterovirus 68 complexed with Michael receptor inhibitor 85
Template:ABSTRACT PUBMED 23388726
Function
[A1E4A3_9ENTO] Protein 2C associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity).[SAAS:SAAS000199_004_016611] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266] RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047]
About this Structure
3zvf is a 1 chain structure with sequence from Human enterovirus 68. Full crystallographic information is available from OCA.
