4iar
From Proteopedia
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{{STRUCTURE_4iar| PDB=4iar | SCENE= }} | {{STRUCTURE_4iar| PDB=4iar | SCENE= }} | ||
| - | ===Crystal structure of the chimeric protein of 5-HT1B-BRIL in complex with ergotamine (PSI Community Target | + | ===Crystal structure of the chimeric protein of 5-HT1B-BRIL in complex with ergotamine (PSI Community Target)=== |
| + | {{ABSTRACT_PUBMED_23519210}} | ||
| + | |||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/5HT1B_HUMAN 5HT1B_HUMAN]] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. | ||
==About this Structure== | ==About this Structure== | ||
Revision as of 21:48, 10 April 2013
Crystal structure of the chimeric protein of 5-HT1B-BRIL in complex with ergotamine (PSI Community Target)
Template:ABSTRACT PUBMED 23519210
Function
[5HT1B_HUMAN] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.
About this Structure
4iar is a 1 chain structure. Full crystallographic information is available from OCA.
Categories: Bai, F. | Cherezov, V. | GPCR, GPCR Network. | Gao, X. | Han, G W. | Huang, X. | Jiang, H. | Jiang, Y. | Katritch, V. | Liu, W. | Ma, J. | McCorvy, J D. | Melcher, K. | Roth, B L. | Stevens, R C. | Vardy, E. | Wacker, D. | Wang, C. | Wu, H. | Xu, H E. | Yang, H. | Yang, L. | Zhang, C. | Zhou, E X. | Electron transport | Ergotamine | Gpcr | Gpcr dock | Gpcr network | Membrane protein | Novel protein engineering | Psi-biology | Signaling protein | Structural genomic
