3zff
From Proteopedia
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{{STRUCTURE_3zff| PDB=3zff | SCENE= }} | {{STRUCTURE_3zff| PDB=3zff | SCENE= }} | ||
===Human enterovirus 71 in complex with capsid binding inhibitor WIN51711=== | ===Human enterovirus 71 in complex with capsid binding inhibitor WIN51711=== | ||
| + | {{ABSTRACT_PUBMED_23509286}} | ||
==Function== | ==Function== | ||
Revision as of 21:49, 10 April 2013
Human enterovirus 71 in complex with capsid binding inhibitor WIN51711
Template:ABSTRACT PUBMED 23509286
Function
[A9X4C2_9ENTO] Protein 2C associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity).[SAAS:SAAS000199_004_016611] Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266] RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047]
About this Structure
3zff is a 4 chain structure with sequence from Human enterovirus 71. Full crystallographic information is available from OCA.
Categories: Human enterovirus 71 | Cardosa, J. | Kuhn, R J. | Perera, R. | Plevka, P. | Rossmann, M G. | Yap, M L. | Capsid | Inhibitor | Picornavirus | Virus
