4hno
From Proteopedia
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| - | [[Image:4hno.png|left|200px]] | ||
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{{STRUCTURE_4hno| PDB=4hno | SCENE= }} | {{STRUCTURE_4hno| PDB=4hno | SCENE= }} | ||
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===High resolution crystal structure of DNA Apurinic/apyrimidinic (AP) endonuclease IV Nfo from Thermatoga maritima=== | ===High resolution crystal structure of DNA Apurinic/apyrimidinic (AP) endonuclease IV Nfo from Thermatoga maritima=== | ||
| + | {{ABSTRACT_PUBMED_23355472}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/END4_THEMA END4_THEMA]] Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity). | ||
==About this Structure== | ==About this Structure== | ||
Revision as of 21:54, 10 April 2013
High resolution crystal structure of DNA Apurinic/apyrimidinic (AP) endonuclease IV Nfo from Thermatoga maritima
Template:ABSTRACT PUBMED 23355472
Function
[END4_THEMA] Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity).
About this Structure
4hno is a 1 chain structure with sequence from Thermotoga maritima msb8. Full crystallographic information is available from OCA.
