3mex

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[[Image:3mex.png|left|200px]]
 
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{{STRUCTURE_3mex| PDB=3mex | SCENE= }}
{{STRUCTURE_3mex| PDB=3mex | SCENE= }}
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===Crystal structure of MexR in oxidized state===
===Crystal structure of MexR in oxidized state===
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{{ABSTRACT_PUBMED_20616806}}
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==Function==
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[[http://www.uniprot.org/uniprot/MEXR_PSEAE MEXR_PSEAE]] Repressor of the mexAB-oprM multidrug resistance operon. Also represses its own expression. Many variants lead to increased expression of the mexAB-oprM operon.
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{{ABSTRACT_PUBMED_20616806}}
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==About this Structure==
==About this Structure==
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3MEX is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MEX OCA].
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[[3mex]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MEX OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:20616806</ref><references group="xtra"/>
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<ref group="xtra">PMID:020616806</ref><references group="xtra"/><references/>
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Chen, H.]]
[[Category: Chen, H.]]
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[[Category: Transcription]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Sep 10 13:29:36 2010''
 

Revision as of 23:02, 10 April 2013

Template:STRUCTURE 3mex

Contents

Crystal structure of MexR in oxidized state

Template:ABSTRACT PUBMED 20616806

Function

[MEXR_PSEAE] Repressor of the mexAB-oprM multidrug resistance operon. Also represses its own expression. Many variants lead to increased expression of the mexAB-oprM operon.

About this Structure

3mex is a 2 chain structure with sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.

Reference

  • Chen H, Yi C, Zhang J, Zhang W, Ge Z, Yang CG, He C. Structural insight into the oxidation-sensing mechanism of the antibiotic resistance of regulator MexR. EMBO Rep. 2010 Sep;11(9):685-90. Epub 2010 Jul 9. PMID:20616806 doi:10.1038/embor.2010.96

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