This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3mex
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
| - | [[Image:3mex.png|left|200px]] | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3mex", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3mex| PDB=3mex | SCENE= }} | {{STRUCTURE_3mex| PDB=3mex | SCENE= }} | ||
| - | |||
===Crystal structure of MexR in oxidized state=== | ===Crystal structure of MexR in oxidized state=== | ||
| + | {{ABSTRACT_PUBMED_20616806}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/MEXR_PSEAE MEXR_PSEAE]] Repressor of the mexAB-oprM multidrug resistance operon. Also represses its own expression. Many variants lead to increased expression of the mexAB-oprM operon. | |
| - | + | ||
| - | + | ||
| - | - | + | |
| - | + | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3mex]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MEX OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020616806</ref><references group="xtra"/><references/> |
[[Category: Pseudomonas aeruginosa]] | [[Category: Pseudomonas aeruginosa]] | ||
[[Category: Chen, H.]] | [[Category: Chen, H.]] | ||
| Line 37: | Line 24: | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Transcription regulation]] | [[Category: Transcription regulation]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Sep 10 13:29:36 2010'' | ||
Revision as of 23:02, 10 April 2013
Contents |
Crystal structure of MexR in oxidized state
Template:ABSTRACT PUBMED 20616806
Function
[MEXR_PSEAE] Repressor of the mexAB-oprM multidrug resistance operon. Also represses its own expression. Many variants lead to increased expression of the mexAB-oprM operon.
About this Structure
3mex is a 2 chain structure with sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.
Reference
- Chen H, Yi C, Zhang J, Zhang W, Ge Z, Yang CG, He C. Structural insight into the oxidation-sensing mechanism of the antibiotic resistance of regulator MexR. EMBO Rep. 2010 Sep;11(9):685-90. Epub 2010 Jul 9. PMID:20616806 doi:10.1038/embor.2010.96
