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3mb5
From Proteopedia
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{{STRUCTURE_3mb5| PDB=3mb5 | SCENE= }} | {{STRUCTURE_3mb5| PDB=3mb5 | SCENE= }} | ||
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===Crystal structure of P. abyssi tRNA m1A58 methyltransferase in complex with S-adenosyl-L-methionine=== | ===Crystal structure of P. abyssi tRNA m1A58 methyltransferase in complex with S-adenosyl-L-methionine=== | ||
| + | {{ABSTRACT_PUBMED_20483913}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/Q9V1J7_PYRAB Q9V1J7_PYRAB]] Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenosine at position(s) 57 (m1A57) and 58 (m1A58) in the T-loop of some tRNAs. Methylates the first adenine of an AA sequence.<ref>PMID:14739239</ref> <ref>PMID:20483913</ref> | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020483913</ref><ref group="xtra">PMID:014739239</ref><references group="xtra"/><references/> |
[[Category: Pyrococcus abyssi]] | [[Category: Pyrococcus abyssi]] | ||
[[Category: Golinelli-Pimpaneau, B.]] | [[Category: Golinelli-Pimpaneau, B.]] | ||
Revision as of 23:03, 10 April 2013
Contents |
Crystal structure of P. abyssi tRNA m1A58 methyltransferase in complex with S-adenosyl-L-methionine
Template:ABSTRACT PUBMED 20483913
Function
[Q9V1J7_PYRAB] Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenosine at position(s) 57 (m1A57) and 58 (m1A58) in the T-loop of some tRNAs. Methylates the first adenine of an AA sequence.[1] [2]
About this Structure
3mb5 is a 1 chain structure with sequence from Pyrococcus abyssi. Full crystallographic information is available from OCA.
Reference
- Guelorget A, Roovers M, Guerineau V, Barbey C, Li X, Golinelli-Pimpaneau B. Insights into the hyperthermostability and unusual region-specificity of archaeal Pyrococcus abyssi tRNA m1A57/58 methyltransferase. Nucleic Acids Res. 2010 May 18. PMID:20483913 doi:10.1093/nar/gkq381
- Roovers M, Wouters J, Bujnicki JM, Tricot C, Stalon V, Grosjean H, Droogmans L. A primordial RNA modification enzyme: the case of tRNA (m1A) methyltransferase. Nucleic Acids Res. 2004 Jan 22;32(2):465-76. Print 2004. PMID:14739239 doi:10.1093/nar/gkh191
- ↑ Roovers M, Wouters J, Bujnicki JM, Tricot C, Stalon V, Grosjean H, Droogmans L. A primordial RNA modification enzyme: the case of tRNA (m1A) methyltransferase. Nucleic Acids Res. 2004 Jan 22;32(2):465-76. Print 2004. PMID:14739239 doi:10.1093/nar/gkh191
- ↑ Guelorget A, Roovers M, Guerineau V, Barbey C, Li X, Golinelli-Pimpaneau B. Insights into the hyperthermostability and unusual region-specificity of archaeal Pyrococcus abyssi tRNA m1A57/58 methyltransferase. Nucleic Acids Res. 2010 May 18. PMID:20483913 doi:10.1093/nar/gkq381
