3mb5

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[[Image:3mb5.png|left|200px]]
 
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{{STRUCTURE_3mb5| PDB=3mb5 | SCENE= }}
{{STRUCTURE_3mb5| PDB=3mb5 | SCENE= }}
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===Crystal structure of P. abyssi tRNA m1A58 methyltransferase in complex with S-adenosyl-L-methionine===
===Crystal structure of P. abyssi tRNA m1A58 methyltransferase in complex with S-adenosyl-L-methionine===
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{{ABSTRACT_PUBMED_20483913}}
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==Function==
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[[http://www.uniprot.org/uniprot/Q9V1J7_PYRAB Q9V1J7_PYRAB]] Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenosine at position(s) 57 (m1A57) and 58 (m1A58) in the T-loop of some tRNAs. Methylates the first adenine of an AA sequence.<ref>PMID:14739239</ref> <ref>PMID:20483913</ref>
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{{ABSTRACT_PUBMED_20483913}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:20483913</ref><ref group="xtra">PMID:14739239</ref><references group="xtra"/>
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<ref group="xtra">PMID:020483913</ref><ref group="xtra">PMID:014739239</ref><references group="xtra"/><references/>
[[Category: Pyrococcus abyssi]]
[[Category: Pyrococcus abyssi]]
[[Category: Golinelli-Pimpaneau, B.]]
[[Category: Golinelli-Pimpaneau, B.]]

Revision as of 23:03, 10 April 2013

Template:STRUCTURE 3mb5

Contents

Crystal structure of P. abyssi tRNA m1A58 methyltransferase in complex with S-adenosyl-L-methionine

Template:ABSTRACT PUBMED 20483913

Function

[Q9V1J7_PYRAB] Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenosine at position(s) 57 (m1A57) and 58 (m1A58) in the T-loop of some tRNAs. Methylates the first adenine of an AA sequence.[1] [2]

About this Structure

3mb5 is a 1 chain structure with sequence from Pyrococcus abyssi. Full crystallographic information is available from OCA.

Reference

  • Guelorget A, Roovers M, Guerineau V, Barbey C, Li X, Golinelli-Pimpaneau B. Insights into the hyperthermostability and unusual region-specificity of archaeal Pyrococcus abyssi tRNA m1A57/58 methyltransferase. Nucleic Acids Res. 2010 May 18. PMID:20483913 doi:10.1093/nar/gkq381
  • Roovers M, Wouters J, Bujnicki JM, Tricot C, Stalon V, Grosjean H, Droogmans L. A primordial RNA modification enzyme: the case of tRNA (m1A) methyltransferase. Nucleic Acids Res. 2004 Jan 22;32(2):465-76. Print 2004. PMID:14739239 doi:10.1093/nar/gkh191
  1. Roovers M, Wouters J, Bujnicki JM, Tricot C, Stalon V, Grosjean H, Droogmans L. A primordial RNA modification enzyme: the case of tRNA (m1A) methyltransferase. Nucleic Acids Res. 2004 Jan 22;32(2):465-76. Print 2004. PMID:14739239 doi:10.1093/nar/gkh191
  2. Guelorget A, Roovers M, Guerineau V, Barbey C, Li X, Golinelli-Pimpaneau B. Insights into the hyperthermostability and unusual region-specificity of archaeal Pyrococcus abyssi tRNA m1A57/58 methyltransferase. Nucleic Acids Res. 2010 May 18. PMID:20483913 doi:10.1093/nar/gkq381

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