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3m66
From Proteopedia
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{{STRUCTURE_3m66| PDB=3m66 | SCENE= }} | {{STRUCTURE_3m66| PDB=3m66 | SCENE= }} | ||
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===Crystal structure of human Mitochondrial Transcription Termination Factor 3=== | ===Crystal structure of human Mitochondrial Transcription Termination Factor 3=== | ||
| + | {{ABSTRACT_PUBMED_20430012}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/MTER1_HUMAN MTER1_HUMAN]] Binds promoter DNA and regulates initiation of transcription. Required for normal mitochondrial transcription, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function (By similarity).<ref>PMID:17662942</ref> | |
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3m66]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M66 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020430012</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Gustafsson, C M.]] | [[Category: Gustafsson, C M.]] | ||
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[[Category: Transcription termination]] | [[Category: Transcription termination]] | ||
[[Category: Transit peptide]] | [[Category: Transit peptide]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 12 10:29:35 2010'' | ||
Revision as of 23:03, 10 April 2013
Contents |
Crystal structure of human Mitochondrial Transcription Termination Factor 3
Template:ABSTRACT PUBMED 20430012
Function
[MTER1_HUMAN] Binds promoter DNA and regulates initiation of transcription. Required for normal mitochondrial transcription, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function (By similarity).[1]
About this Structure
3m66 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Spahr H, Samuelsson T, Hallberg BM, Gustafsson CM. Structure of mitochondrial transcription termination factor 3 reveals a novel nucleic acid-binding domain. Biochem Biophys Res Commun. 2010 Jul 2;397(3):386-90. Epub 2010 Apr 27. PMID:20430012 doi:10.1016/j.bbrc.2010.04.130
- ↑ Park CB, Asin-Cayuela J, Camara Y, Shi Y, Pellegrini M, Gaspari M, Wibom R, Hultenby K, Erdjument-Bromage H, Tempst P, Falkenberg M, Gustafsson CM, Larsson NG. MTERF3 is a negative regulator of mammalian mtDNA transcription. Cell. 2007 Jul 27;130(2):273-85. PMID:17662942 doi:10.1016/j.cell.2007.05.046
